HAMAP rule MF_00149
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00149 |
| Accession | MF_00149 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 19) |
| Name | DNA_mis_repair |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P23367 (MUTL_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00149 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MUTL |
| Protein name | RecName: Full=DNA mismatch repair protein MutL; |
| Gene name | Name=mutL; |
Comments
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| FUNCTION | This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. |
| SIMILARITY | Belongs to the DNA mismatch repair MutL/HexB family. |
Keywords
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Gene Ontology
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| GO:0006298; Biological process:mismatch repair |
Cross-references
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| Pfam | PF01119; DNA_mis_repair; 1; |
| Pfam | PF02518; HATPase_c; 1; |
| NCBIfam | TIGR00585; Mutl; 1; |
| PROSITE | PS00058; DNA_MISMATCH_REPAIR_1; 1; |
Features
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Additional information
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| Size range | 425-674 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |