HAMAP

Accession	MF_00162
Dates	1-JUN-2001 (Created) 16-AUG-2010 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00162; [distribution of match scores in UniProtKB];[seed alignment for MF_00162]

Names

GSH-S

Identifier

GSHB

Protein name

RecName: Full=Glutathione synthetase; EC=6.3.2.3; AltName: Full=GSH synthetase; Short=GSH-S; Short=GSHase; AltName: Full=Glutathione synthase;

Gene name

gshB

CATALYTIC ACTIVITY: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.

PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.

SIMILARITY: Belongs to the prokaryotic GSH synthase family.

Pfam	PF02955; GSH-S_ATP; 1; PF02951; GSH-S_N; 1;
PROSITE	PS50975; ATP_GRASP; 1; trigger=PRU00409;

Glutathione biosynthesis, Ligase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004363; Molecular function: glutathione synthase activity.
GO:0006750; Biological process: glutathione biosynthetic process.

Size range:	307-324 amino acids
Related UniRules:	None
Template:	P04425 (GSHB_ECOLI); O32463 (GSHB_SYNE7): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None