Annotation rule MF_00162
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General rule information [?]

Accession MF_00162
Dates 1-JUN-2001 (Created)
27-NOV-2013 (Last updated, Version 21)
Name GSH_S
Scope Bacteria

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GSHB
Protein name
RecName: Full=Glutathione synthetase;
EC=6.3.2.3;
AltName: Full=GSH synthetase;
Short=GSH-S;
Short=GSHase;
AltName: Full=Glutathione synthase;
Gene name
gshB

Comments [?]

Catalytic activity ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.
Pathway Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate; step 2/2.
Similarity Belongs to the prokaryotic GSH synthase family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004363; Molecular function: glutathione synthase activity.
GO:0006750; Biological process: glutathione biosynthetic process.

Cross-references [?]

Pfam PF02955; GSH-S_ATP; 1;
PF02951; GSH-S_N; 1;
PROSITE PS50975; ATP_GRASP; 1; trigger=PRU00409;

Additional information [?]

Size range 307-324 amino acids
Related rules None
Templates P04425 (GSHB_ECOLI); O32463 (GSHB_SYNE7): [Recover all]
Fusion None