HAMAP

Accession	MF_00167
Dates	1-JUN-2001 (Created) 18-MAY-2011 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_00167; [distribution of match scores in UniProtKB];[seed alignment for MF_00167]

Names

CsrA

Identifier

CSRA

Protein name

RecName: Full=Carbon storage regulator;

Protein name

RecName: Full=Carbon storage regulator homolog;

Gene name

csrA

FUNCTION: Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity).

FUNCTION: Affects glycogen biosynthesis, gluconeogenesis, cell size and surface properties. Regulates glycogen synthesis under both aerobic and anaerobic conditions. Seems to accelerate the degradation of glg gene transcripts, potentially through selective RNA binding. Acts to inhibit interaction between the letD protein and the A subunit of DNA gyrase. Also required for motility and flagellum biosynthesis through the post-transcriptional activation of flhDC expression. This involves binding to and stabilization of the flhDC message by csrA (By similarity).

SUBUNIT: Homodimer. Binds to the csrB RNA which antagonizes the activity of csrA (By similarity).

SIMILARITY: Belongs to the CsrA family.

Pfam	PF02599; CsrA; 1;
TIGRFAMs	TIGR00202; CsrA; 1;

RNA-binding.

GO:0003723; Molecular function: RNA binding.
GO:0006402; Biological process: mRNA catabolic process.
GO:0006109; Biological process: regulation of carbohydrate metabolic process.

Size range:	57-85 amino acids
Related UniRules:	None
Template:	P69913 (CSRA_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in COXBU, PSESM
Plasmid encoded:	None