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HAMAP rule MF_00170

General rule information [?]

Accession	MF_00170
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25)
Name	Rib_5P_isom_A
Scope(s)	Bacteria Archaea
Template(s)	P0A7Z0 (RPIA_ECOLI); O50083 (RPIA_PYRHO); Q72J47 (RPIA_THET2); Q58998 (RPIA_METJA); [ Recover all ]
Triggered by	HAMAP; MF_00170 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RPIA
Protein name	RecName: Full=Ribose-5-phosphate isomerase A; EC=5.3.1.6; AltName: Full=Phosphoriboisomerase A; Short=PRI;
Gene name	Name=rpiA;

Comments [?]

FUNCTION	Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
CATALYTIC ACTIVITY	Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate; Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273; EC=5.3.1.6;
PATHWAY	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
SUBUNIT	Homodimer.
SIMILARITY	Belongs to the ribose 5-phosphate isomerase family.

Keywords [?]

Gene Ontology [?]

GO:0004751; Molecular function:ribose-5-phosphate isomerase activity

GO:0009052; Biological process:pentose-phosphate shunt, non-oxidative branch

Cross-references [?]

Features [?]

From: RPIA_ECOLI (P0A7Z0)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="substrate"

x-G-x-T

BINDING

/ligand="substrate"

D-x-x-D

BINDING

/ligand="substrate"

K-G-x-G

ACT_SITE

103

/note="Proton acceptor"

BINDING

121

/ligand="substrate"

[KR]

Additional information [?]