HAMAP logo

HAMAP rule MF_00195

Send feedback

General rule information [?]

Accession MF_00195
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 30)
Name GTPase_Der
Scope(s) Bacteria
Template(s) Q9X1F8 (DER_THEMA); P0A6P5 (DER_ECOLI); P50743 (DER_BACSU); [ Recover all ]
Triggered by HAMAP; MF_00195 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DER
Protein name RecName: Full=GTPase Der;
AltName: Full=GTP-binding protein EngA;
Gene name Name=der;

Comments [?]

FUNCTIONGTPase that plays an essential role in the late steps of ribosome biogenesis.
SUBUNITAssociates with the 50S ribosomal subunit.
SIMILARITYBelongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

Keywords [?]


Gene Ontology [?]

GO:0005525; Molecular function:GTP binding

Cross-references [?]

Pfam PF01926; MMR_HSR1; 1;
PIRSF PIRSF006485; GTP-binding_EngA; 1;
PRINTS PR00326; GTP1OBG; 1;
PRINTS PR00449; RASTRNSFRMNG; 1;
NCBIfam TIGR03594; GTPase_EngA; 1;
NCBIfam TIGR00231; Small_GTP; 2;
PROSITE PS51712; G_ENGA; 2;

Features [?]

From: DER_ECOLI (P0A6P5)
Key From To Description Tag Condition FTGroup
BINDING 9 16 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="1"
G-x(2)-N-V-G-K-S
BINDING 56 60 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="1"
D-[ST]-x-G-x
BINDING 118 121 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="1"
N-K-x-[DE]
BINDING 209 216 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="2"
G-x(2)-N-x-G-K-S
BINDING 256 260 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="2"
D-T-[AP]-G-x
BINDING 321 324 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="2"
[NS]-K-x-D
From: DER_THEMA (Q9X1F8)
Key From To Description Tag Condition FTGroup
DOMAIN 357 439 /note="KH-like"

Additional information [?]

Size range 433-552 amino acids
Related rules None
Fusion Nter: None Cter: None



View rule in raw text format (no links)