HAMAP

Accession	MF_00195
Dates	1-JUN-2001 (Created) 18-MAY-2011 (Last updated, Version 23)

Data class

Protein

Predictors

HAMAP; MF_00195; [distribution of match scores in UniProtKB];[seed alignment for MF_00195]

Names

GTPase_Der

Identifier

DER

Protein name

RecName: Full=GTPase Der; AltName: Full=GTP-binding protein EngA;

Gene name

der

FUNCTION: GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity).

SUBUNIT: Associates with the 50S ribosomal subunit (By similarity).

SIMILARITY: Belongs to the Era/MnmE GTP-binding protein family. Der subfamily.

SIMILARITY: Contains 1 KH-like domain.

Pfam	PF01926; MMR_HSR1; 1; trigger=Yes;
PIRSF	PIRSF006485; GTP-binding_EngA; 1;
PRINTS	PR00326; GTP1OBG; 1; PR00449; RASTRNSFRMNG; 1;
TIGRFAMs	TIGR03594; GTPase_EngA; 1; TIGR00231; Small_GTP; 2;

GTP-binding, Nucleotide-binding, Ribosome biogenesis.

GO:0005525; Molecular function: GTP binding.

From: DER_ECOLI (P0A6P5)
Key		From		To		Description		Condition		FTGroup
NP_BIND		9		16		GTP 1 (Potential)		G-x(2)-N-V-G-K-S
NP_BIND		56		60		GTP 1 (Potential)		D-[ST]-x-G-x
NP_BIND		118		121		GTP 1 (Potential)		N-K-x-[DE]
NP_BIND		209		216		GTP 2 (Potential)		G-x(2)-N-x-G-K-S
NP_BIND		256		260		GTP 2 (Potential)		D-T-[AP]-G-x
NP_BIND		321		324		GTP 2 (Potential)		[NS]-K-x-D
From: DER_THEMA (Q9X1F8)
DOMAIN		357		439		KH-like

Size range:	433-552 amino acids
Related UniRules:	None
Template:	Q9X1F8 (DER_THEMA); P0A6P5 (DER_ECOLI); P50743 (DER_BACSU): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	in RHIME