HAMAP rule MF_00195
General rule information
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| Accession | MF_00195 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 30) |
| Name | GTPase_Der |
| Scope(s) |
Bacteria |
| Template(s) | Q9X1F8 (DER_THEMA); P0A6P5 (DER_ECOLI); P50743 (DER_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00195 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | DER |
| Protein name | RecName: Full=GTPase Der; AltName: Full=GTP-binding protein EngA; |
| Gene name | Name=der; |
Comments
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| FUNCTION | GTPase that plays an essential role in the late steps of ribosome biogenesis. |
| SUBUNIT | Associates with the 50S ribosomal subunit. |
| SIMILARITY | Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. |
Keywords
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Gene Ontology
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| GO:0005525; Molecular function:GTP binding |
Cross-references
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| Pfam | PF01926; MMR_HSR1; 1; |
| PIRSF | PIRSF006485; GTP-binding_EngA; 1; |
| PRINTS | PR00326; GTP1OBG; 1; |
| PRINTS | PR00449; RASTRNSFRMNG; 1; |
| NCBIfam | TIGR03594; GTPase_EngA; 1; |
| NCBIfam | TIGR00231; Small_GTP; 2; |
| PROSITE | PS51712; G_ENGA; 2; |
Features
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| From: DER_ECOLI (P0A6P5) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 9 | 16 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="1" |
G-x(2)-N-V-G-K-S | ||||||||
| BINDING | 56 | 60 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="1" |
D-[ST]-x-G-x | ||||||||
| BINDING | 118 | 121 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="1" |
N-K-x-[DE] | ||||||||
| BINDING | 209 | 216 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="2" |
G-x(2)-N-x-G-K-S | ||||||||
| BINDING | 256 | 260 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="2" |
D-T-[AP]-G-x | ||||||||
| BINDING | 321 | 324 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="2" |
[NS]-K-x-D | ||||||||
| From: DER_THEMA (Q9X1F8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | 357 | 439 | /note="KH-like" | |||||||||
Additional information
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| Size range | 433-552 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |