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HAMAP rule MF_00203

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General rule information [?]

Accession MF_00203
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 29)
Name UvrC
Scope(s) Bacteria
Archaea
Template(s) P0A8G0 (UVRC_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00203 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier UVRC
Protein name RecName: Full=UvrABC system protein C;
                 Short=Protein UvrC;
AltName: Full=Excinuclease ABC subunit C;
Gene name Name=uvrC;

Comments [?]

FUNCTIONThe UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
SUBUNITInteracts with UvrB in an incision complex.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the UvrC family.

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0009381; Molecular function:excinuclease ABC activity
GO:0006281; Biological process:DNA repair
GO:0006289; Biological process:nucleotide-excision repair
GO:0009432; Biological process:SOS response
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01541; GIY-YIG; 1;
Pfam PF02151; UVR; 1;
Pfam PF08459; UvrC_HhH_N; 1;
NCBIfam TIGR00194; UvrC; 1;
PROSITE PS50164; GIY_YIG; 1;
PROSITE PS50151; UVR; 0-1;
PROSITE PS50165; UVRC; 1;

Features [?]


Additional information [?]

Size range 519-747 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Weird insertions in STRCO and TREPA



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