HAMAP

Accession	MF_00203
Dates	1-JUN-2001 (Created) 18-AUG-2011 (Last updated, Version 24)

Data class

Protein

Predictors

HAMAP; MF_00203; [distribution of match scores in UniProtKB];[seed alignment for MF_00203]

Names

UvrC

Identifier

UVRC

Protein name

RecName: Full=UvrABC system protein C; Short=Protein UvrC; AltName: Full=Excinuclease ABC subunit C;

Gene name

uvrC

FUNCTION: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity).

SUBUNIT: Interacts with UvrB in an incision complex (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the UvrC family.

SIMILARITY: Contains 1 UVR domain.

Pfam	PF01541; GIY-YIG; 1; PF02151; UVR; 1; PF08459; UvrC_HhH_N; 1;
TIGRFAMs	TIGR00194; UvrC; 1;
PROSITE	PS50151; UVR; 0-1; trigger=PRU00217; PS50164; UVRC_1; 1; PS50165; UVRC_2; 1;

Cytoplasm, DNA damage, SOS response, Excision nuclease, DNA repair, DNA excision.

GO:0003677; Molecular function: DNA binding.
GO:0009381; Molecular function: excinuclease ABC activity.
GO:0006281; Biological process: DNA repair.
GO:0006289; Biological process: nucleotide-excision repair.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.

Size range:	519-747 amino acids
Related UniRules:	None
Template:	P0A8G0 (UVRC_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Weird insertions in STRCO and TREPA