HAMAP

Accession	MF_00207
Dates	1-JUN-2001 (Created) 9-DEC-2011 (Last updated, Version 19)

Data class

Protein

Predictors

HAMAP; MF_00207; [distribution of match scores in UniProtKB];[seed alignment for MF_00207]

Names

PPase_C

Identifier

PPAC

Protein name

RecName: Full=Probable manganese-dependent inorganic pyrophosphatase; EC=3.6.1.1; AltName: Full=Pyrophosphate phospho-hydrolase; Short=PPase;

Gene name

ppaC

CATALYTIC ACTIVITY: Diphosphate + H(2)O = 2 phosphate.

COFACTOR: Binds 2 manganese ions per subunit (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the PPase class C family.

Pfam	PF01368; DHH; 1; PF02833; DHHA2; 1;

Cytoplasm, Hydrolase.

Manganese, Metal-binding.

GO:0004427; Molecular function: inorganic diphosphatase activity.
GO:0030145; Molecular function: manganese ion binding.
GO:0005737; Cellular component: cytoplasm.

From: PPAC_BACSU (P37487)
Key		From		To		Description		Condition		FTGroup
METAL		9		9		Manganese 1 (By similarity)		H		1
METAL		13		13		Manganese 1 (By similarity)		D		1
METAL		15		15		Manganese 2 (By similarity)		D		1
METAL		75		75		Manganese 1 (By similarity)		D		1
METAL		75		75		Manganese 2 (By similarity)		D		1
METAL		97		97		Manganese 2 (By similarity)		H		1
METAL		149		149		Manganese 2 (By similarity)		D		1

Size range:	307-336 amino acids
Related UniRules:	None
Template:	P37487 (PPAC_BACSU); Q58025 (PPAC_METJA): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	The sequence of ppaC in THEMA is interrupted by a 130-residue insert that contains 2 CBS domains.