HAMAP

Accession	MF_00210
Dates	1-JUN-2001 (Created) 9-DEC-2011 (Last updated, Version 39)

Data class

Protein

Predictors

HAMAP; MF_00210; [distribution of match scores in UniProtKB];[seed alignment for MF_00210]

Names

EPSP_synth

Identifier

AROA

Protein name

RecName: Full=3-phosphoshikimate 1-carboxyvinyltransferase; EC=2.5.1.19; AltName: Full=5-enolpyruvylshikimate-3-phosphate synthase; Short=EPSP synthase; Short=EPSPS;

Protein name

RecName: Full=Probable 3-phosphoshikimate 1-carboxyvinyltransferase; EC=2.5.1.19; AltName: Full=5-enolpyruvylshikimate-3-phosphate synthase; Short=EPSP synthase; Short=EPSPS;

Gene name

aroA

CATALYTIC ACTIVITY: Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.

PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

SUBUNIT: Monomer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the EPSP synthase family.

Pfam	PF00275; EPSP_synthase; 1;
PIRSF	PIRSF000505; EPSPS; 1;
TIGRFAMs	TIGR01356; AroA; 1;
PROSITE	PS00104; EPSP_SYNTHASE_1; 1; PS00885; EPSP_SYNTHASE_2; 1;

Cytoplasm, Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Transferase.

GO:0003866; Molecular function: 3-phosphoshikimate 1-carboxyvinyltransferase activity.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	408-455 amino acids
Related UniRules:	None
Template:	P0A6D3 (AROA_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Highly divergent AERSA; sequence not included in alignment. Divergent duplicate aroA sequence in AERPE: APE1404. Possible wrong start in SYNY3, THEMA.