HAMAP

Accession	MF_00217
Dates	1-JUN-2001 (Created) 19-MAY-2011 (Last updated, Version 19)

Data class

Protein

Predictors

HAMAP; MF_00217; [distribution of match scores in UniProtKB];[seed alignment for MF_00217]

Names

Mevalonate_kinase

Identifier

KIME

Protein name

RecName: Full=Mevalonate kinase; Short=MK; EC=2.7.1.36;

Gene name

mvk

CATALYTIC ACTIVITY: ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate.

COFACTOR: Magnesium (By similarity).

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

Pfam	PF08544; GHMP_kinases_C; 1; PF00288; GHMP_kinases_N; 1;
PRINTS	PR00959; MEVGALKINASE; 1;
TIGRFAMs	TIGR00549; Mevalon_kin; 1;
PROSITE	PS00627; GHMP_KINASES_ATP; 1;

Cytoplasm, Transferase, Kinase, ATP-binding, Nucleotide-binding, Magnesium.

GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0004496; Molecular function: mevalonate kinase activity.
GO:0005737; Cellular component: cytoplasm.

From: KIME_METJA (Q58487)
Key		From		To		Description		Condition		FTGroup
NP_BIND		104		114		ATP (Potential)		P-x(3)-G-L-G-S-S-A-[SA]

Size range:	284-337 amino acids
Related UniRules:	MF_00384 (KHSE)
Template:	Q58487 (KIME_METJA)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None