Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP annotation rule: MF_00221
Send feedback new

General rule information

Accession MF_00221
Dates 1-JUN-2001 (Created)
19-MAY-2011 (Last updated, Version 35)
Data class Protein
Predictors HAMAP; MF_00221; [distribution of match scores in UniProtKB];[seed alignment for MF_00221]
Names MntH


Propagated annotation

Identifier, protein and gene names
Identifier MNTH

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Protein name
RecName: Full=Manganese transport protein mntH;

else
Protein name
RecName: Full=Probable manganese transport protein mntH;
end case

Gene name mntH
Comments
FUNCTION: H(+)-stimulated, highly selective, manganese uptake system (By similarity).

case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case

SIMILARITY: Belongs to the NRAMP family.
Cross-references
Pfam PF01566; Nramp; 1;
PRINTS PR00447; NATRESASSCMP; 1;
TIGRFAMs TIGR01197; Nramp; 1;
Keywords

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane.
end case

Cell membrane, Manganese, Membrane, Symport, Transmembrane, Transport, Transmembrane helix.
Gene Ontology
GO:0030145; Molecular function: manganese ion binding.
GO:0015293; Molecular function: symporter activity.
GO:0006828; Biological process: manganese ion transport.
GO:0005886; Cellular component: plasma membrane.
Features

case not defined <Property:Membrane> or <Property:Membrane=1>
From: MNTH_BACSU (P96593)
Key     From     To       Description   Condition   FTGroup
TOPO_DOM     Nter     25       Cytoplasmic (Potential)      
TRANSMEM     26     45       Helical; (Potential)      
TOPO_DOM     46     59       Extracellular (Potential)      
TRANSMEM     60     82       Helical; (Potential)      
TOPO_DOM     83     106       Cytoplasmic (Potential)      
TRANSMEM     107     129       Helical; (Potential)      
TOPO_DOM     130     132       Extracellular (Potential)      
TRANSMEM     133     155       Helical; (Potential)      
TOPO_DOM     156     167       Cytoplasmic (Potential)      
TRANSMEM     168     187       Helical; (Potential)      
TOPO_DOM     188     208       Extracellular (Potential)      
TRANSMEM     209     231       Helical; (Potential)      
TOPO_DOM     232     254       Cytoplasmic (Potential)      
TRANSMEM     255     277       Helical; (Potential)      
TOPO_DOM     278     296       Extracellular (Potential)      
TRANSMEM     297     319       Helical; (Potential)      
TOPO_DOM     320     338       Cytoplasmic (Potential)      
TRANSMEM     339     358       Helical; (Potential)      
TOPO_DOM     359     362       Extracellular (Potential)      
TRANSMEM     363     385       Helical; (Potential)      
TOPO_DOM     386     397       Cytoplasmic (Potential)      
TRANSMEM     398     420       Helical; (Potential)      
TOPO_DOM     421     Cter       Extracellular (Potential)      
end case

case defined <Property:Membrane> and <Property:Membrane=2>
From: MNTH_ECOLI (P0A769)
Key     From     To       Description   Condition   FTGroup
TOPO_DOM     Nter     19       Cytoplasmic (Potential)      
TRANSMEM     20     39       Helical; (Potential)      
TOPO_DOM     40     51       Periplasmic (Potential)      
TRANSMEM     52     71       Helical; (Potential)      
TOPO_DOM     72     95       Cytoplasmic (Potential)      
TRANSMEM     96     118       Helical; (Potential)      
TOPO_DOM     119     125       Periplasmic (Potential)      
TRANSMEM     126     145       Helical; (Potential)      
TOPO_DOM     146     155       Cytoplasmic (Potential)      
TRANSMEM     156     175       Helical; (Potential)      
TOPO_DOM     176     196       Periplasmic (Potential)      
TRANSMEM     197     220       Helical; (Potential)      
TOPO_DOM     221     238       Cytoplasmic (Potential)      
TRANSMEM     239     258       Helical; (Potential)      
TOPO_DOM     259     276       Periplasmic (Potential)      
TRANSMEM     277     297       Helical; (Potential)      
TOPO_DOM     298     327       Cytoplasmic (Potential)      
TRANSMEM     328     344       Helical; (Potential)      
TOPO_DOM     345     350       Periplasmic (Potential)      
TRANSMEM     351     370       Helical; (Potential)      
TOPO_DOM     371     387       Cytoplasmic (Potential)      
TRANSMEM     388     406       Helical; (Potential)      
TOPO_DOM     407     Cter       Periplasmic (Potential)      
end case



Additional information

Size range: 409-472 amino acids
Related UniRules: None
Template: P96593 (MNTH_BACSU); P0A769 (MNTH_ECOLI): [Recover all]
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: in PSEAE
Plasmid encoded: None
Comments: Probable wrong starts in AGRT5, XYLFA, XYLFT

View rule in raw text format (no links)



UniProtKB rule member sequences