HAMAP

Accession	MF_00231
Dates	1-JUN-2001 (Created) 17-AUG-2010 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_00231; [distribution of match scores in UniProtKB];[seed alignment for MF_00231]

Names

eIF-2-alpha

Identifier

IF2A

Protein name

RecName: Full=Translation initiation factor 2 subunit alpha; AltName: Full=aIF2-alpha; AltName: Full=eIF-2-alpha;

Gene name

eif2a

FUNCTION: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).

SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain (By similarity).

SIMILARITY: Belongs to the eIF-2-alpha family.

SIMILARITY: Contains 1 S1 motif domain.

Pfam	PF00575; S1; 1;
PROSITE	PS50126; S1; 1; trigger=PRU00180;

Initiation factor, Protein biosynthesis, RNA-binding.

GO:0003723; Molecular function: RNA binding.
GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.

Size range:	254-277 amino acids
Related UniRules:	None
Template:	P20459 (IF2A_YEAST)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None