HAMAP

Accession	MF_00236
Dates	1-JUN-2001 (Created) 11-OCT-2011 (Last updated, Version 34)

Data class

Protein

Predictors

HAMAP; MF_00236; [distribution of match scores in UniProtKB];[seed alignment for MF_00236]

Names

TatA_E

Identifier

TATA

Protein name

RecName: Full=Sec-independent protein translocase protein TatA;

Gene name

tatA

FUNCTION: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity).

SUBUNIT: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon (By similarity).

SUBUNIT: Forms a complex with TatC (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane protein (By similarity).

SIMILARITY: Belongs to the TatA/E family.

Pfam	PF02416; MttA_Hcf106; 1;
TIGRFAMs	TIGR01411; TatAE; 1;
General	Transmembrane; -; 1; trigger=Yes;

Cell inner membrane.

Cell membrane, Transport, Protein transport, Translocation, Membrane, Transmembrane, Transmembrane helix.

GO:0008320; Molecular function: protein transmembrane transporter activity.
GO:0043953; Biological process: protein transport by the Tat complex.
GO:0005887; Cellular component: integral to plasma membrane.
GO:0033281; Cellular component: TAT protein transport complex.

Size range:	53-105 amino acids
Related UniRules:	MF_00903 (TATE (supersedes the current rule))
Template:	P69428 (TATA_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in AQUAE, BACSU
Plasmid encoded:	None
Comments:	Presence of a second copy called TatE in many Enterobacteriaceae. TatA and TatE are functionally equivalent to each other. TatE may be a cryptic gene duplication of tatA. Profile MF_00236 matches both TatA and TatE.