HAMAP rule MF_00237
General rule information
[?]
Accession | MF_00237 |
Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 41) |
Name | TatB |
Scope(s) |
Bacteria |
Template(s) | P69425 (TATB_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00237 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | TATB |
case <OC:Pseudomonadota> or <OC:Actinomycetota> | |
RecName: Full=Sec-independent protein translocase protein TatB; | |
Gene name | Name=tatB; |
else | |
RecName: Full=Sec-independent protein translocase protein TatB homolog; | |
end case |
Comments
[?]
case <OC:Pseudomonadota> or <OC:Actinomycetota> | |
FUNCTION | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. |
SUBUNIT | The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. |
end case | |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the TatB family. |
Keywords
[?]
case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Cell membrane | |
Membrane | |
Protein transport | |
Transport | |
Translocation | |
Transmembrane | |
Transmembrane helix |
Gene Ontology
[?]
GO:0008320; Molecular function:protein transmembrane transporter activity |
GO:0043953; Biological process:protein transport by the Tat complex |
GO:0005886; Cellular component:plasma membrane |
GO:0033281; Cellular component:TAT protein transport complex |
Cross-references
[?]
Features
[?]
From: TATB_ECOLI (P69425) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TRANSMEM | 1 | 21 | /note="Helical" |
Additional information
[?]
Size range | 110-246 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | The Tat system is composed of TatA, TatB and TatC subunits in Gram-negative bacteria and in Actinomycetota, and of TatA and TatC subunits in most Gram-positive bacteria. |