Annotation rule MF_00238
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General rule information [?]

Accession MF_00238
Dates 1-JUN-2001 (Created)
26-SEP-2014 (Last updated, Version 27)
Name Cytidyl_kinase_type1
Scope Bacteria; except Cyanobacteria
Templates P0A6I0 (KCY_ECOLI); P38493 (KCY_BACSU); P9WPA9 (KCY_MYCTU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KCY
Protein name
RecName: Full=Cytidylate kinase;
Short=CK;
EC=2.7.4.25;
AltName: Full=Cytidine monophosphate kinase;
Short=CMP kinase;
Gene name
cmk

Comments [?]

Catalytic activity ATP + (d)CMP = ADP + (d)CDP.
Subcellular location Cytoplasm.
Similarity Belongs to the cytidylate kinase family. Type 1 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004127; Molecular function: cytidylate kinase activity.
GO:0006220; Biological process: pyrimidine nucleotide metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02224; Cytidylate_kin; 1;
TIGRFAMs TIGR00017; Cmk; 1;

Features [?]

From: KCY_ECOLI (P0A6I0)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     12     20       ATP     G-x(2)-[GSA]-x-G-K-[GST]-[STAV]  

Additional information [?]

Size range 206-235 amino acids
Related rules MF_00239 (KCY); MF_01349 (PANCY supersedes the current rule)
Fusion None
Comments In Cyanobacteria this protein is fused N-terminally to pantoate-- beta-alanine ligase (see MF_01349). BORBU and BORGA also have a subfamily 2 enzyme.