HAMAP

Accession	MF_00238
Dates	1-JUN-2001 (Created) 7-NOV-2011 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00238; [distribution of match scores in UniProtKB];[seed alignment for MF_00238]

Names

Cytidyl_kinase_type1

Identifier

KCY

Protein name

RecName: Full=Cytidylate kinase; Short=CK; EC=2.7.4.25; AltName: Full=Cytidine monophosphate kinase; Short=CMP kinase;

Gene name

cmk

CATALYTIC ACTIVITY: ATP + (d)CMP = ADP + (d)CDP.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the cytidylate kinase family. Type 1 subfamily.

Pfam	PF02224; Cytidylate_kin; 1;
TIGRFAMs	TIGR00017; Cmk; 1;

Cytoplasm, Transferase, Kinase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004127; Molecular function: cytidylate kinase activity.
GO:0006220; Biological process: pyrimidine nucleotide metabolic process.
GO:0005737; Cellular component: cytoplasm.

From: KCY_ECOLI (P0A6I0)
Key		From		To		Description		Condition		FTGroup
NP_BIND		12		20		ATP (By similarity)		G-x(2)-[GSA]-x-G-K-[GST]-[STAV]

Size range:	206-235 amino acids
Related UniRules:	MF_00239 (KCY); MF_01349 (PANCY (supersedes the current rule))
Template:	P0A6I0 (KCY_ECOLI); P38493 (KCY_BACSU); P63803 (KCY_MYCTU): [Recover all]
Scope:	Bacteria; except Cyanobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in HAEIN
Plasmid encoded:	None
Comments:	In Cyanobacteria this protein is fused N-terminally to pantoate-- beta-alanine ligase (see MF_01349). BORBU and BORGA also have a subfamily 2 enzyme.