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HAMAP rule MF_00239

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General rule information [?]

Accession MF_00239
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 32)
Name Cytidyl_kinase_type2
Scope(s) Bacteria
Archaea
Template(s) P0A6I0 (KCY_ECOLI); P38493 (KCY_BACSU); [ Recover all ]
Triggered by HAMAP; MF_00239 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier KCY
Protein name RecName: Full=Cytidylate kinase;
                 Short=CK;
                 EC=2.7.4.25;
AltName: Full=Cytidine monophosphate kinase;
                 Short=CMP kinase;
Gene name Name=cmk;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + CMP = ADP + CDP; Xref=Rhea:RHEA:11600, ChEBI:CHEBI:30616, ChEBI:CHEBI:58069, ChEBI:CHEBI:60377, ChEBI:CHEBI:456216; EC=2.7.4.25;
CATALYTIC ACTIVITY Reaction=ATP + dCMP = ADP + dCDP; Xref=Rhea:RHEA:25094, ChEBI:CHEBI:30616, ChEBI:CHEBI:57566, ChEBI:CHEBI:58593, ChEBI:CHEBI:456216; EC=2.7.4.25;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the cytidylate kinase family. Type 2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004127; Molecular function:cytidylate kinase activity
GO:0006220; Biological process:pyrimidine nucleotide metabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02224; Cytidylate_kin; 1;
NCBIfam TIGR02173; Cyt_kin_arch; 1;

Features [?]

From: KCY_METJA (Q58071)
Key From To Description Tag Condition FTGroup
BINDING 7 15 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
G-x(2)-G-x-G-x-[ST]-[ST]

Additional information [?]

Size range 161-193 amino acids
Related rules MF_00238
Fusion Nter: None Cter: None
Comments Generally found in archaea, but also present in a few bacterial species BORBU and BORGP also have a subfamily 1 enzyme



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