HAMAP

Accession	MF_00240
Dates	1-JUN-2001 (Created) 20-MAY-2011 (Last updated, Version 15)

Data class

Protein

Predictors

HAMAP; MF_00240; [distribution of match scores in UniProtKB];[seed alignment for MF_00240]

Names

LolA

Identifier

LOLA

Protein name

RecName: Full=Outer-membrane lipoprotein carrier protein; Flags: Precursor;

Gene name

lolA

FUNCTION: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).

SUBUNIT: Monomer (By similarity).

SUBCELLULAR LOCATION: Periplasm (By similarity).

SIMILARITY: Belongs to the lolA family.

Pfam	PF03548; LolA; 1;
TIGRFAMs	TIGR00547; LolA; 1;
General	Signal; -; 1; trigger=Yes;

Chaperone, Transport, Protein transport, Periplasm, Signal.

GO:0008565; Molecular function: protein transporter activity.
GO:0015031; Biological process: protein transport.
GO:0042597; Cellular component: periplasmic space.

Size range:	169-215 amino acids
Related UniRules:	None
Template:	P61316 (LOLA_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	The epsilon proteobacteria possess lolA but apparently they do not have lolB. Further characterization is needed to assess to which protein the outer membrane lipoproteins are translocated (the same applies to the animal symbionts Candidatus Blochmannia floridanus and Wigglesworthia glossinidia brevipalpis).