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Annotation rule MF_00240
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General rule information [?]

Accession MF_00240
Dates 1-JUN-2001 (Created)
26-SEP-2014 (Last updated, Version 17)
Name LolA
Scope Bacteria; Proteobacteria
Template P61316 (LOLA_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
LOLA
Protein name
RecName: Full=Outer-membrane lipoprotein carrier protein;
Flags: Precursor;
Gene name
lolA

Comments [?]

Function Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
Subunit Monomer.
Subcellular location Periplasm.
Similarity Belongs to the LolA family.

Keywords [?]


Gene Ontology [?]

GO:0008565; Molecular function: protein transporter activity.
GO:0015031; Biological process: protein transport.
GO:0042597; Cellular component: periplasmic space.

Cross-references [?]

Pfam PF03548; LolA; 1;
TIGRFAMs TIGR00547; LolA; 1;

Computed features [?]

General Signal; -; 1; trigger=yes;

Additional information [?]

Size range 169-215 amino acids
Related rules None
Fusion None
Comments The epsilon proteobacteria possess lolA but apparently they do not have lolB. Further characterization is needed to assess to which protein the outer membrane lipoproteins are translocated (the same applies to the animal symbionts Candidatus Blochmannia floridanus and Wigglesworthia glossinidia brevipalpis).