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HAMAP rule MF_00242

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General rule information [?]

Accession MF_00242
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 31)
Name Arg_deiminase
Scope(s) Bacteria
Template(s) O53088 (ARCA_LATSK); [ Recover all ]
Triggered by HAMAP; MF_00242 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ARCA
Protein name RecName: Full=Arginine deiminase;
                 Short=ADI;
                 EC=3.5.3.6;
AltName: Full=Arginine dihydrolase;
                 Short=AD;
Gene name Name=arcA;

Comments [?]

CATALYTIC ACTIVITY Reaction=H2O + L-arginine = L-citrulline + NH4(+); Xref=Rhea:RHEA:19597, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32682, ChEBI:CHEBI:57743; EC=3.5.3.6;
PATHWAYAmino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 1/2.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the arginine deiminase family.

Keywords [?]


Gene Ontology [?]

GO:0016990; Molecular function:arginine deiminase activity
GO:0006527; Biological process:arginine catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02274; Amidinotransf; 1;
PIRSF PIRSF006356; Arg_deiminase; 1;
PRINTS PR01466; ARGDEIMINASE; 1;
NCBIfam TIGR01078; ArcA; 1;

Features [?]

From: ARCA_LATSK (O53088)
Key From To Description Tag Condition FTGroup
ACT_SITE 399 399 /note="Amidino-cysteine intermediate" C

Additional information [?]

Size range 402-420 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments There is a divergent second copy of arcA in MYCPN. The first copy shown here is a reconstruction and could be artefactual



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