HAMAP

Accession	MF_00243
Dates	1-JUN-2001 (Created) 20-MAY-2011 (Last updated, Version 27)

Data class

Protein

Predictors

HAMAP; MF_00243; [distribution of match scores in UniProtKB];[seed alignment for MF_00243]

Names

NMN_adenylyltr

Identifier

NADM

Protein name

RecName: Full=Nicotinamide-nucleotide adenylyltransferase; EC=2.7.7.1; AltName: Full=NAD(+) diphosphorylase; AltName: Full=NAD(+) pyrophosphorylase; AltName: Full=NMN adenylyltransferase;

CATALYTIC ACTIVITY: ATP + nicotinamide ribonucleotide = diphosphate + NAD(+).

PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the archaeal NMN adenylyltransferase family.

Pfam	PF01467; CTP_transf_2; 1;
TIGRFAMs	TIGR01527; Arch_NMN_Atrans; 1; TIGR00125; Cyt_tran_rel; 1;

ATP-binding, Cytoplasm, NAD, Nucleotide-binding, Nucleotidyltransferase, Pyridine nucleotide biosynthesis, Transferase.

GO:0000309; Molecular function: nicotinamide-nucleotide adenylyltransferase activity.
GO:0009435; Biological process: NAD biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	168-188 amino acids
Related UniRules:	None
Template:	Q57961 (NADM_METJA); O26253 (NADM_METTH): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: <Nudix>
Duplicate:	in AERPE, ARCFU
Plasmid encoded:	None
Comments:	There are closely related homolog of nadD in ARCFU (AF1488) and AERPE (APE1986). Nudix-like C-terminal domain in SYNY3.