HAMAP

Accession	MF_00246
Dates	1-JUN-2001 (Created) 9-JUN-2011 (Last updated, Version 24)

Data class

Protein

Predictors

HAMAP; MF_00246; [distribution of match scores in UniProtKB];[seed alignment for MF_00246]

Names

Galactokinase

Identifier

GAL1

Protein name

RecName: Full=Galactokinase; EC=2.7.1.6; AltName: Full=Galactose kinase;

Gene name

galK

CATALYTIC ACTIVITY: ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate.

PATHWAY: Carbohydrate metabolism; galactose metabolism.

SUBCELLULAR LOCATION: Cytoplasm (Potential).

SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.

Pfam	PF10509; GalKase_gal_bdg; 1; PF08544; GHMP_kinases_C; 1; PF00288; GHMP_kinases_N; 1;
PIRSF	PIRSF000530; Galactokinase; 1;
PRINTS	PR00473; GALCTOKINASE; 1; PR00959; MEVGALKINASE; 1;
TIGRFAMs	TIGR00131; Gal_kin; 1;
PROSITE	PS00106; GALACTOKINASE; 1; PS00627; GHMP_KINASES_ATP; 1;

Cytoplasm, Transferase, Kinase, Carbohydrate metabolism, Galactose metabolism, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004335; Molecular function: galactokinase activity.
GO:0006012; Biological process: galactose metabolic process.
GO:0005737; Cellular component: cytoplasm.

From: GAL1_ECOLI (P0A6T3)
Key		From		To		Description		Condition		FTGroup
NP_BIND		122		132		ATP (Potential)		x(2)-[GSA](3)-L-S-S-S-[SA](2)

Size range:	350-399 amino acids
Related UniRules:	None
Template:	P0A6T3 (GAL1_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Divergent galK in TREPA: TP0418; not included in alignment