HAMAP

Accession	MF_00247
Dates	1-JUN-2001 (Created) 9-DEC-2011 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00247; [distribution of match scores in UniProtKB];[seed alignment for MF_00247]

Names

SthA

Identifier

STHA

Protein name

RecName: Full=Soluble pyridine nucleotide transhydrogenase; Short=STH; EC=1.6.1.1; AltName: Full=NAD(P)(+) transhydrogenase [B-specific];

Gene name

sthA, udhA

Gene name

sthA

FUNCTION: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity).

CATALYTIC ACTIVITY: NADPH + NAD(+) = NADP(+) + NADH.

COFACTOR: Binds 1 FAD per subunit (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

Pfam	PF00070; Pyr_redox; 1; PF07992; Pyr_redox_2; 1; PF02852; Pyr_redox_dim; 1;
PRINTS	PR00368; FADPNR; 1; PR00945; HGRDTASE; 1;

Cytoplasm, Oxidoreductase, Flavoprotein, FAD, NADP, NAD.

GO:0003957; Molecular function: NAD(P)+ transhydrogenase (B-specific) activity.
GO:0006739; Biological process: NADP metabolic process.
GO:0005737; Cellular component: cytoplasm.

From: STHA_ECOLI (P27306)
Key		From		To		Description		Condition		FTGroup
NP_BIND		36		45		FAD (By similarity)

Size range:	463-471 amino acids
Related UniRules:	None
Template:	P27306 (STHA_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None