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HAMAP rule MF_00254

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General rule information [?]

Accession MF_00254
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 26)
Name Gly_tRNA_synth_alpha
Scope(s) Bacteria
Template(s) O23627 (SYGM1_ARATH); [ Recover all ]
Triggered by HAMAP; MF_00254 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier SYGA
Protein name RecName: Full=Glycine--tRNA ligase alpha subunit;
                 EC=6.1.1.14;
AltName: Full=Glycyl-tRNA synthetase alpha subunit;
                 Short=GlyRS;
Gene name Name=glyQ;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl- tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA- COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305, ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215; EC=6.1.1.14;
SUBUNITTetramer of two alpha and two beta subunits.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the class-II aminoacyl-tRNA synthetase family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004820; Molecular function:glycine-tRNA ligase activity
GO:0006426; Biological process:glycyl-tRNA aminoacylation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02091; tRNA-synt_2e; 1;
PRINTS PR01044; TRNASYNTHGA; 1;
NCBIfam TIGR00388; GlyQ; 1;
PROSITE PS50861; AA_TRNA_LIGASE_II_GLYAB; 1;

Features [?]


Additional information [?]

Size range 285-319 amino acids
Related rules None
Fusion Nter: None Cter: MF_00255 (glyS)
Comments glyQ and glyS are fused in Chlamydia. Possible wrong start in XYLFA.



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