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HAMAP annotation rule: MF_00283
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General rule information

Accession MF_00283
Dates 1-JUN-2001 (Created)
21-NOV-2011 (Last updated, Version 35)
Data class Protein
Predictors HAMAP; MF_00283; [distribution of match scores in UniProtKB];[seed alignment for MF_00283]
Names Phe_tRNA_synth_beta1


Propagated annotation

Identifier, protein and gene names
Identifier SYFB

case not <OG:Chloroplast>
Protein name
RecName: Full=Phenylalanine--tRNA ligase beta chain;
EC=6.1.1.20;
AltName: Full=Phenylalanyl-tRNA synthetase beta chain;
Short=PheRS;

else case <OG:Chloroplast>
Protein name
RecName: Full=Phenylalanine--tRNA ligase beta chain, chloroplastic;
EC=6.1.1.20;
AltName: Full=Phenylalanyl-tRNA synthetase beta chain;
Short=PheRS;
end case

Gene name pheT
Comments
CATALYTIC ACTIVITY: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
COFACTOR: Binds 2 magnesium ions per tetramer (By similarity).
SUBUNIT: Tetramer of two alpha and two beta chains (By similarity).

case <OC:Bacteria>
SUBCELLULAR LOCATION: Cytoplasm (By similarity).

else case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the phenylalanyl-tRNA synthetase beta chain family. Type 1 subfamily.

case <Feature:PS50886>
SIMILARITY: Contains 1 tRNA-binding domain.
end case

Cross-references
Pfam PF01588; tRNA_bind; 1;
TIGRFAMs TIGR00471; PheT_arch; 1;
TIGR00472; PheT_bact; 1;
PROSITE PS51483; B5; 1; trigger=PRU00816;
PS50886; TRBD; 0-1; trigger=PRU00209;
PS51447; FDX_ACB; 0-1; trigger=PRU00778;
Keywords

case <OC:Bacteria>
Cytoplasm.
end case

Aminoacyl-tRNA synthetase, Protein biosynthesis, Ligase, ATP-binding, Nucleotide-binding, Magnesium, Metal-binding.

case <Feature:PS50886>
RNA-binding, tRNA-binding.
end case

Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0004826; Molecular function: phenylalanine-tRNA ligase activity.

case <Feature:PS50886>
GO:0003723; Molecular function: RNA binding.
GO:0000049; Molecular function: tRNA binding.
end case

GO:0006432; Biological process: phenylalanyl-tRNA aminoacylation.

case <OC:Bacteria>
GO:0005737; Cellular component: cytoplasm.

else case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Features
From: SYFB_THETH (P27002)
Key     From     To       Description   Condition   FTGroup
METAL     452     452       Magnesium (By similarity)   D  
METAL     458     458       Magnesium; via carbonyl oxygen (By similarity)   D  
METAL     461     461       Magnesium (By similarity)   E  
METAL     462     462       Magnesium (By similarity)   [ED]  


Additional information

Size range: 706-869 amino acids
Related UniRules: None
Template: P27002 (SYFB_THETH)
Scope: Bacteria
Plastid
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences