HAMAP

Accession	MF_00286
Dates	1-JUN-2001 (Created) 2-DEC-2010 (Last updated, Version 40)

Data class

Protein

Predictors

HAMAP; MF_00286; [distribution of match scores in UniProtKB];[seed alignment for MF_00286]

Names

DsbB

Identifier

DSBB

Protein name

RecName: Full=Disulfide bond formation protein B; AltName: Full=Disulfide oxidoreductase;

Gene name

dsbB

FUNCTION: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).

SIMILARITY: Belongs to the DsbB family.

Pfam	PF02600; DsbB; 1;

Cell inner membrane.

Cell membrane, Disulfide bond, Oxidoreductase, Redox-active center, Transport, Electron transport, Chaperone, Transmembrane, Membrane, Transmembrane helix.

GO:0009055; Molecular function: electron carrier activity.
GO:0015035; Molecular function: protein disulfide oxidoreductase activity.
GO:0005886; Cellular component: plasma membrane.
GO:0055114; Biological process: oxidation-reduction process.

From: DSBB_ECOLI (P0A6M2)
Key		From		To		Description		Condition		FTGroup
TOPO_DOM		Nter		14		Cytoplasmic (Potential)
TRANSMEM		15		31		Helical; (Potential)
TOPO_DOM		32		49		Periplasmic (Potential)
TRANSMEM		50		65		Helical; (Potential)
TOPO_DOM		66		71		Cytoplasmic (Potential)
TRANSMEM		72		89		Helical; (Potential)
TOPO_DOM		90		144		Periplasmic (Potential)
TRANSMEM		145		163		Helical; (Potential)
TOPO_DOM		164		Cter		Cytoplasmic (Potential)
DISULFID		41		44		Redox-active (By similarity)		C-x-x-C
DISULFID		104		130		Redox-active (By similarity)		C-x*-C

Size range:	158-185 amino acids
Related UniRules:	MF_00287 (BDBC); MF_01311 (DSBI)
Template:	P0A6M2 (DSBB_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in BURS3, PSEAB, PSEAE, PSEE4, PSEF5, PSEPF, PSE14, PSEPU, PSEU2
Plasmid encoded:	None