HAMAP rule MF_00286
General rule information
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Accession | MF_00286 |
Dates | 1-JUN-2001 (Created)
3-JUN-2021 (Last updated, Version 46) |
Name | DsbB |
Scope(s) |
Bacteria |
Template(s) | P0A6M2 (DSBB_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00286 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | DSBB |
Protein name | RecName: Full=Disulfide bond formation protein B; AltName: Full=Disulfide oxidoreductase; |
Gene name | Name=dsbB; |
Comments
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FUNCTION | Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the DsbB family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Cell membrane | |
Disulfide bond | |
Oxidoreductase | |
Redox-active center | |
Transport | |
Electron transport | |
Chaperone | |
Transmembrane | |
Membrane | |
Transmembrane helix |
Gene Ontology
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GO:0009055; Molecular function:electron transfer activity |
GO:0015035; Molecular function:protein-disulfide reductase activity |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF02600; DsbB; 1; |
Features
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From: DSBB_ECOLI (P0A6M2) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 14 | /note="Cytoplasmic" | |||||||||
TRANSMEM | 15 | 31 | /note="Helical" | |||||||||
TOPO_DOM | 32 | 49 | /note="Periplasmic" | |||||||||
TRANSMEM | 50 | 65 | /note="Helical" | |||||||||
TOPO_DOM | 66 | 71 | /note="Cytoplasmic" | |||||||||
TRANSMEM | 72 | 89 | /note="Helical" | |||||||||
TOPO_DOM | 90 | 144 | /note="Periplasmic" | |||||||||
TRANSMEM | 145 | 163 | /note="Helical" | |||||||||
TOPO_DOM | 164 | Cter | /note="Cytoplasmic" | |||||||||
DISULFID | 41 | 44 | /note="Redox-active" | C-x-x-C | ||||||||
DISULFID | 104 | 130 | /note="Redox-active" | C-x*-C |
Additional information
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Size range | 158-185 amino acids |
Related rules |
MF_00287 MF_01311 |
Fusion | Nter: None Cter: None |