HAMAP

Accession	MF_00288
Dates	1-JUN-2001 (Created) 9-DEC-2011 (Last updated, Version 23)

Data class

Protein

Predictors

HAMAP; MF_00288; [distribution of match scores in UniProtKB];[seed alignment for MF_00288]

Names

MetE

Identifier

METE

Protein name

RecName: Full=Probable methylcobalamin:homocysteine methyltransferase; EC=2.1.1.-; AltName: Full=Methionine synthase;

Gene name

metE

FUNCTION: Catalyzes the transfer of a methyl group from methylcobalamin and methylcobinamide to homocysteine resulting in methionine formation (By similarity).

COFACTOR: Binds 1 zinc ion per subunit (By similarity).

PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway.

SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase family.

Pfam	PF01717; Meth_synt_2; 1;

Transferase, Methyltransferase, Amino-acid biosynthesis, Methionine biosynthesis, Metal-binding, Zinc.

GO:0008168; Molecular function: methyltransferase activity.
GO:0009086; Biological process: methionine biosynthetic process.

From: METE_METTH (O26869)
Key		From		To		Description		Condition		FTGroup
METAL		201		201		Zinc (By similarity)		H
METAL		203		203		Zinc (By similarity)		C
METAL		285		285		Zinc (By similarity)		C

Size range:	308-344 amino acids
Related UniRules:	MF_00172 (METE)
Template:	P55299 (METE_METTM)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None