Annotation rule MF_00295
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General rule information [?]

Accession MF_00295
Dates 1-JUN-2001 (Created)
27-NOV-2013 (Last updated, Version 27)
Name Homoser_O_succinyltr
Scope Bacteria

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
META
Protein name
RecName: Full=Homoserine O-succinyltransferase;
EC=2.3.1.46;
AltName: Full=Homoserine O-transsuccinylase;
Short=HTS;
Gene name
metA

Comments [?]

Catalytic activity Succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine.
case <OC:Escherichia>
Enzyme regulation Allosterically inhibited by SAM and methionine (By similarity).
end case
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Subunit Homodimer (By similarity).
end case
Subcellular location Cytoplasm (By similarity).
Similarity Belongs to the HTS family.

Keywords [?]


Gene Ontology [?]

GO:0008899; Molecular function: homoserine O-succinyltransferase activity.
GO:0019281; Biological process: L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF04204; HTS; 1;
TIGRFAMs TIGR01001; MetA; 1;

Features [?]

From: META_ECOLI (P07623)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     142     142       Potential     C  

Additional information [?]

Size range 293-321 amino acids
Related rules None
Template P07623 (META_ECOLI)
Fusion None