HAMAP annotation rule MF_00295
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Accession MF_00295
Dates 1-JUN-2001 (Created)
9-JUN-2011 (Last updated, Version 26)
Name Homoser_O-succinyltr
Scope Bacteria
Triggered by



Identifier
META
Protein name
RecName: Full=Homoserine O-succinyltransferase;
EC=2.3.1.46;
AltName: Full=Homoserine O-transsuccinylase;
Short=HTS;
Gene name
metA


CATALYTIC ACTIVITY Succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine.
case <OC:Escherichia>
ENZYME REGULATION Allosterically inhibited by SAM and methionine (By similarity).
end case
PATHWAY Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-succinyl-L-homoserine from L-homoserine; step 1/1.
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
SUBUNIT Homodimer (By similarity).
end case
SUBCELLULAR LOCATION Cytoplasm (By similarity).
SIMILARITY Belongs to the HTS family.


Cytoplasm
Amino-acid biosynthesis
Methionine biosynthesis
Transferase
Acyltransferase


GO:0008899; Molecular function: homoserine O-succinyltransferase activity.
GO:0019281; Biological process: L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine.
GO:0005737; Cellular component: cytoplasm.


Pfam PF04204; HTS; 1;
TIGRFAMs TIGR01001; MetA; 1;


From: META_ECOLI (P07623)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     142     142       Potential     C  


Size range: 293-321 amino acids
Related Rules: None
Template: P07623 (META_ECOLI)
Fusion: None


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