HAMAP

Accession	MF_00296
Dates	1-JUN-2001 (Created) 9-JUN-2011 (Last updated, Version 30)

Data class

Protein

Predictors

HAMAP; MF_00296; [distribution of match scores in UniProtKB];[seed alignment for MF_00296]

Names

Homoser_O-acetyltr

Identifier

METX

Protein name

RecName: Full=Homoserine O-acetyltransferase; EC=2.3.1.31; AltName: Full=Homoserine O-trans-acetylase; Short=HTA; Short=Homoserine transacetylase;

Gene name

metX

CATALYTIC ACTIVITY: Acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine.

PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the AB hydrolase superfamily. HTA family.

Pfam	PF00561; Abhydrolase_1; 1;
PIRSF	PIRSF000443; Homoser_Ac_trans; 1;
TIGRFAMs	TIGR01392; HomoserO_Ac_trn; 1;

Cytoplasm, Amino-acid biosynthesis, Methionine biosynthesis, Transferase, Acyltransferase.

GO:0004414; Molecular function: homoserine O-acetyltransferase activity.
GO:0009086; Biological process: methionine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: METX_HAEIN (P45131)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		143		143		Potential		S
ACT_SITE		337		337		Potential		H

Size range:	334-445 amino acids
Related UniRules:	None
Template:	P45131 (METX_HAEIN)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Divergent possible metX in METTH: MTH_1820. Possible wrong starts in DEIRA, HALSA, RALSO and THETH.