HAMAP

Accession	MF_00297
Dates	1-JUN-2001 (Created) 2-NOV-2010 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00297; [distribution of match scores in UniProtKB];[seed alignment for MF_00297]

Names

Nudix_NudC

Identifier

NUDC

Protein name

RecName: Full=NADH pyrophosphatase; EC=3.6.1.22;

Gene name

nudC

CATALYTIC ACTIVITY: NAD(+) + H(2)O = AMP + NMN.

COFACTOR: Divalent metal cations. Magnesium or manganese (By similarity).

COFACTOR: Binds 1 zinc ion per subunit (By similarity).

SUBUNIT: Homodimer (By similarity).

SIMILARITY: Belongs to the Nudix hydrolase family. NudC subfamily.

Pfam	PF00293; NUDIX; 1; PF09296; NUDIX-like; 1; PF09297; zf-NADH-PPase; 1;
PRINTS	PR00502; NUDIXFAMILY; 1;
PROSITE	PS51462; NUDIX; 1; trigger=PRU00794; PS00893; NUDIX_BOX; 1;

Hydrolase, NAD, Magnesium, Manganese, Metal-binding.

Zinc.

GO:0000210; Molecular function: NAD+ diphosphatase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0030145; Molecular function: manganese ion binding.

GO:0008270; Molecular function: zinc ion binding.

From: NUDC_ECOLI (P32664)
Key		From		To		Description		Condition		FTGroup
MOTIF		159		180		Nudix box
METAL (Optional)		98		98		Zinc (By similarity)		C
METAL (Optional)		101		101		Zinc (By similarity)		C
METAL (Optional)		116		116		Zinc (By similarity)		C
METAL (Optional)		119		119		Zinc (By similarity)		C
METAL		174		174		Divalent metal cation (By similarity)		E
METAL		178		178		Divalent metal cation (By similarity)		E

Size range:	257-313 amino acids
Related UniRules:	None
Template:	P32664 (NUDC_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong start in MYCTU