HAMAP

Accession	MF_00300
Dates	1-JUN-2001 (Created) 9-JUN-2011 (Last updated, Version 29)

Data class

Protein

Predictors

HAMAP; MF_00300; [distribution of match scores in UniProtKB];[seed alignment for MF_00300]

Names

Chorismate_synth

Identifier

AROC

Protein name

RecName: Full=Chorismate synthase; EC=4.2.3.5; AltName: Full=5-enolpyruvylshikimate-3-phosphate phospholyase;

Gene name

aroC

CATALYTIC ACTIVITY: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.

COFACTOR: Reduced flavin (By similarity).

PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.

SUBUNIT: Homotetramer (By similarity).

SIMILARITY: Belongs to the chorismate synthase family.

Pfam	PF01264; Chorismate_synt; 1;
PIRSF	PIRSF001456; Chorismate_synth; 1;
TIGRFAMs	TIGR00033; AroC; 1;
PROSITE	PS00787; CHORISMATE_SYNTHASE_1; 1; PS00788; CHORISMATE_SYNTHASE_2; 1; PS00789; CHORISMATE_SYNTHASE_3; 1;

Lyase, Amino-acid biosynthesis, Aromatic amino acid biosynthesis.

GO:0004107; Molecular function: chorismate synthase activity.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.

Size range:	330-422 amino acids
Related UniRules:	None
Template:	P12008 (AROC_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None