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HAMAP annotation rule: MF_00301
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General rule information

Accession MF_00301
Dates 1-JUN-2001 (Created)
9-JUN-2011 (Last updated, Version 20)
Data class Protein
Predictors HAMAP; MF_00301; [distribution of match scores in UniProtKB];[seed alignment for MF_00301]
Names Homoser_kinase_2


Propagated annotation

Identifier, protein and gene names
Identifier KHSE
Protein name
RecName: Full=Homoserine kinase;
Short=HK;
Short=HSK;
EC=2.7.1.39;
Gene name thrB
Comments
CATALYTIC ACTIVITY: ATP + L-homoserine = ADP + O-phospho-L-homoserine.
PATHWAY: Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.
SIMILARITY: Belongs to the pseudomonas-type thrB family.
Cross-references
Pfam PF01636; APH; 1;
TIGRFAMs TIGR00938; ThrB_alt; 1;
Keywords
Amino-acid biosynthesis, ATP-binding, Kinase, Nucleotide-binding, Threonine biosynthesis, Transferase.
Gene Ontology
GO:0004413; Molecular function: homoserine kinase activity.
GO:0009088; Biological process: threonine biosynthetic process.


Additional information

Size range: 305-334 amino acids
Related UniRules: None
Template: P29364 (KHSE_PSEAE); Q9RAM6 (KHSE_METFK): [Recover all]
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None
Comments: Other species have a classical-type thrB

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UniProtKB rule member sequences