HAMAP

Accession	MF_00306
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00306; [distribution of match scores in UniProtKB];[seed alignment for MF_00306]

Names

SRP54

Identifier

SRP54

Protein name

RecName: Full=Signal recognition 54 kDa protein; AltName: Full=SRP54;

Gene name

srp54

FUNCTION: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes (By similarity).

SUBUNIT: Archaeal signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19 (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

DOMAIN: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence (By similarity).

SIMILARITY: Belongs to the GTP-binding SRP family.

Pfam	PF00448; SRP54; 1; PF02881; SRP54_N; 1; PF02978; SRP_SPB; 1;
PROSITE	PS00300; SRP54; 1;

Cytoplasm, Signal recognition particle, GTP-binding, Nucleotide-binding, Ribonucleoprotein, RNA-binding.

GO:0008312; Molecular function: 7S RNA binding.
GO:0005525; Molecular function: GTP binding.
GO:0005737; Cellular component: cytoplasm.

From: SRP54_METJA (Q57565)
Key		From		To		Description		Condition		FTGroup
NP_BIND		107		114		GTP (By similarity)		G-x-x-G-x-G-K-T
NP_BIND		188		192		GTP (By similarity)		D-[ST]-[AS]-G-R
NP_BIND		247		250		GTP (By similarity)		x-K-x-D
REGION		Nter		294		G-domain
REGION		295		Cter		M-domain

Size range:	431-469 amino acids
Related UniRules:	None
Template:	O29633 (SRP54_ARCFU)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None