HAMAP rule MF_00317
General rule information
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| Accession | MF_00317 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 19) |
| Name | DNApol_clamp_arch |
| Scope(s) |
Archaea |
| Template(s) | O73947 (PCNA_PYRFU); P57765 (PCNA3_SACS2); P57766 (PCNA1_SACS2); Q97Z84 (PCNA2_SACS2); Q975N2 (PCNA1_SULTO); Q975M2 (PCNA2_SULTO); Q973F5 (PCNA3_SULTO); [ Recover all ] |
| Triggered by |
HAMAP; MF_00317 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PCNA |
| Protein name | RecName: Full=DNA polymerase sliding clamp; AltName: Full=Proliferating cell nuclear antigen homolog; Short=PCNA; |
| Gene name | Name=pcn; |
Comments
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| FUNCTION | Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. |
| SUBUNIT | Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA. |
| SIMILARITY | Belongs to the PCNA family. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0030337; Molecular function:DNA polymerase processivity factor activity |
| GO:0006275; Biological process:regulation of DNA replication |
Cross-references
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| Pfam | PF02747; PCNA_C; 1; |
| Pfam | PF00705; PCNA_N; 1; |
| PRINTS | PR00339; PCNACYCLIN; 1; |
| NCBIfam | TIGR00590; Pcna; 1; |
| PROSITE | PS01251; PCNA_1; 1; |
| PROSITE | PS00293; PCNA_2; 1; |
Features
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Additional information
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| Size range | 244-256 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Some Archaea have up to 3 copies. |