HAMAP rule MF_00319
General rule information
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Accession | MF_00319 |
Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35) |
Name | Cdh |
Scope(s) |
Bacteria |
Template(s) | P06282 (CDH_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00319 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | CDH |
Protein name | RecName: Full=CDP-diacylglycerol pyrophosphatase; EC=3.6.1.26; AltName: Full=CDP-diacylglycerol phosphatidylhydrolase; AltName: Full=CDP-diglyceride hydrolase; |
Gene name | Name=cdh; |
Comments
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CATALYTIC ACTIVITY | Reaction=a CDP-1,2-diacyl-sn-glycerol + H2O = a 1,2-diacyl-sn-glycero- 3-phosphate + CMP + 2 H(+); Xref=Rhea:RHEA:15221, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:58332, ChEBI:CHEBI:58608, ChEBI:CHEBI:60377; EC=3.6.1.26; |
PATHWAY | Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the Cdh family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Cell membrane | |
Hydrolase | |
Lipid biosynthesis | |
Lipid metabolism | |
Membrane | |
Phospholipid biosynthesis | |
Phospholipid metabolism | |
Transmembrane | |
Transmembrane helix |
Gene Ontology
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GO:0008715; Molecular function:CDP-diacylglycerol diphosphatase activity |
GO:0008654; Biological process:phospholipid biosynthetic process |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF02611; CDH; 1; |
NCBIfam | TIGR00672; Cdh; 1; |
General | Transmembrane; -; 1; |
Features
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Additional information
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Size range | 244-268 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |