HAMAP

Accession	MF_00325
Dates	1-JUN-2001 (Created) 9-DEC-2011 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00325; [distribution of match scores in UniProtKB];[seed alignment for MF_00325]

Names

DNApol_II_A_arch

Identifier

DP2S

Protein name

RecName: Full=DNA polymerase II small subunit; Short=Pol II; EC=2.7.7.7;

Gene name

polB

FUNCTION: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).

CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

CATALYTIC ACTIVITY: Degradation of single-stranded DNA. It acts progressively in a 3'- to 5'-direction, releasing nucleoside 5'-phosphates.

SUBUNIT: Heterodimer of a large subunit and a small subunit (By similarity).

SIMILARITY: Belongs to the DNA polymerase delta/II small subunit family.

Pfam	PF01336; tRNA_anti; 1;

Transferase, Nucleotidyltransferase, DNA-directed DNA polymerase, DNA replication, Hydrolase, Nuclease, Exonuclease, DNA-binding, Multifunctional enzyme.

GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0000738; Biological process: DNA catabolic process, exonucleolytic.
GO:0006261; Biological process: DNA-dependent DNA replication.

Size range:	482-622 amino acids
Related UniRules:	None
Template:	P81412 (DP2S_PYRFU)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None