HAMAP

Accession	MF_00356
Dates	1-JUN-2001 (Created) 19-JUL-2011 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00356; [distribution of match scores in UniProtKB];[seed alignment for MF_00356]

Names

DNApol_PolC

Identifier

DPO3

Protein name

RecName: Full=DNA polymerase III polC-type; Short=PolIII; EC=2.7.7.7;

Gene name

polC

FUNCTION: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).

CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the DNA polymerase type-C family. PolC subfamily.

Pfam	PF07733; DNA_pol3_alpha; 1; PF00929; RNase_T; 1; PF02811; PHP; 1; PF01336; tRNA_anti; 1;
TIGRFAMs	TIGR00573; Dnaq; 1; TIGR01405; PolC_Gram_pos; 1;

Cytoplasm, Transferase, Nucleotidyltransferase, DNA-directed DNA polymerase, DNA replication, Hydrolase, Nuclease, Exonuclease.

GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-dependent DNA replication.
GO:0005737; Cellular component: cytoplasm.

Size range:	1367-1638 amino acids
Related UniRules:	None
Template:	P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	LACLA has a weird insertion not found in other polC.