HAMAP rule MF_00356
General rule information
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Accession | MF_00356 |
Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 32) |
Name | DNApol_PolC |
Scope(s) |
Bacteria |
Template(s) | P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8); [ Recover all ] |
Triggered by |
HAMAP; MF_00356 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | DPO3 |
Protein name | RecName: Full=DNA polymerase III PolC-type; Short=PolIII; EC=2.7.7.7; |
Gene name | Name=polC; |
Comments
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FUNCTION | Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. |
CATALYTIC ACTIVITY | Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112; EC=2.7.7.7; |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the DNA polymerase type-C family. PolC subfamily. |
Keywords
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Cytoplasm |
Transferase |
Nucleotidyltransferase |
DNA-directed DNA polymerase |
DNA replication |
Hydrolase |
Nuclease |
Exonuclease |
Gene Ontology
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GO:0008408; Molecular function:3'-5' exonuclease activity |
GO:0003677; Molecular function:DNA binding |
GO:0003887; Molecular function:DNA-directed DNA polymerase activity |
GO:0006261; Biological process:DNA-templated DNA replication |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Pfam | PF07733; DNA_pol3_alpha; 1; |
Pfam | PF00929; RNase_T; 1; |
Pfam | PF02811; PHP; 1; |
Pfam | PF01336; tRNA_anti; 1; |
NCBIfam | TIGR00573; Dnaq; 1; |
NCBIfam | TIGR01405; PolC_Gram_pos; 1; |
Features
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Additional information
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Size range | 1367-1638 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | LACLA has a weird insertion not found in other polC. |