HAMAP

Accession	MF_00361
Dates	1-JUN-2001 (Created) 13-DEC-2011 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_00361; [distribution of match scores in UniProtKB];[seed alignment for MF_00361]

Names

NAD_kinase

Identifier

PPNK

Protein name

RecName: Full=Probable inorganic polyphosphate/ATP-NAD kinase; Short=Poly(P)/ATP NAD kinase; EC=2.7.1.23;

Gene name

ppnK

FUNCTION: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity).

CATALYTIC ACTIVITY: ATP + NAD(+) = ADP + NADP(+).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

COFACTOR: Divalent metal ions (By similarity).

SIMILARITY: Belongs to the NAD kinase family.

Pfam	PF01513; NAD_kinase; 1;

ATP-binding, Cytoplasm, Kinase, NAD, NADP, Nucleotide-binding, Transferase.

GO:0046872; Molecular function: metal ion binding.
GO:0003951; Molecular function: NAD+ kinase activity.
GO:0005737; Cellular component: cytoplasm.

Size range:	248-363 amino acids
Related UniRules:	None
Template:	P0A5S6 (PPNK_MYCTU)
Scope:	Bacteria Archaea
Fusion:	Nter: <Unknown>; Cter: None
Duplicate:	in NOSS1, BACHD, BACSU, LISIN, LISMO, SYNY3
Plasmid encoded:	None
Comments:	Unknown N-terminal domain in METJA and METMP