HAMAP annotation rule: MF_00383
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Accession MF_00383
Dates 1-JUN-2001 (Created)
19-JUL-2011 (Last updated, Version 25)
Data class Protein
Names TF2B_arch



Identifier TF2B
Protein name
RecName: Full=Transcription initiation factor IIB;
Short=TFIIB;
Gene name tfb
FUNCTION: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) (By similarity).

case <Feature:PS51134>
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
end case

SIMILARITY: Belongs to the TFIIB family.

case <Feature:PS51134>
SIMILARITY: Contains 1 TFIIB-type zinc finger.
end case

Pfam PF00382; TFIIB; 2;
PF08271; TF_Zn_Ribbon; 1;
PRINTS PR00685; TIFACTORIIB; 1;
PROSITE PS00782; TFIIB; 2;
PS51134; ZF_TFIIB; 1; trigger=PRU00469;

case <Feature:PS51134>
end case

GO:0003700; Molecular function: sequence-specific DNA binding transcription factor activity.

case <Feature:PS51134>
GO:0008270; Molecular function: zinc ion binding.
end case

GO:0006355; Biological process: regulation of transcription, DNA-dependent.
GO:0006352; Biological process: transcription initiation, DNA-dependent.
From: TF2B_PYRFU (P61998)
Key     From     To       Description   Condition   FTGroup
REPEAT     114     197       1      
REPEAT     210     291       2      
METAL     7     7       Zinc (By similarity)   C  
METAL     10     10       Zinc (By similarity)   C  
METAL     26     26       Zinc (By similarity)   C  
METAL     29     29       Zinc (By similarity)   C  



Size range: 287-339 amino acids
Related UniRules: None
Template: P61998 (TF2B_PYRFU); P61999 (TF2B_PYRWO): [Recover all]
Scope: Archaea
Fusion: Nter: None; Cter: None
Duplicate: in HALSA, PYRKO, SULSO, THEAC, THEVO
Plasmid encoded: in HALSA
Comments: Intein deleted in METJA

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