HAMAP

Accession	MF_00383
Dates	1-JUN-2001 (Created) 19-JUL-2011 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00383; [distribution of match scores in UniProtKB];[seed alignment for MF_00383]

Names

TF2B_arch

Identifier

TF2B

Protein name

RecName: Full=Transcription initiation factor IIB; Short=TFIIB;

Gene name

tfb

FUNCTION: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) (By similarity).

COFACTOR: Binds 1 zinc ion per subunit (By similarity).

SIMILARITY: Belongs to the TFIIB family.

SIMILARITY: Contains 1 TFIIB-type zinc finger.

Pfam	PF00382; TFIIB; 2; PF08271; TF_Zn_Ribbon; 1;
PRINTS	PR00685; TIFACTORIIB; 1;
PROSITE	PS00782; TFIIB; 2; PS51134; ZF_TFIIB; 1; trigger=PRU00469;

Transcription, Transcription regulation, Repeat.

Metal-binding, Zinc, Zinc-finger.

GO:0003700; Molecular function: sequence-specific DNA binding transcription factor activity.

GO:0008270; Molecular function: zinc ion binding.

GO:0006355; Biological process: regulation of transcription, DNA-dependent.
GO:0006352; Biological process: transcription initiation, DNA-dependent.

From: TF2B_PYRFU (P61998)
Key		From		To		Description		Condition		FTGroup
REPEAT		114		197		1
REPEAT		210		291		2
METAL		7		7		Zinc (By similarity)		C
METAL		10		10		Zinc (By similarity)		C
METAL		26		26		Zinc (By similarity)		C
METAL		29		29		Zinc (By similarity)		C

Size range:	287-339 amino acids
Related UniRules:	None
Template:	P61998 (TF2B_PYRFU); P61999 (TF2B_PYRWO): [Recover all]
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in HALSA, PYRKO, SULSO, THEAC, THEVO
Plasmid encoded:	in HALSA
Comments:	Intein deleted in METJA