HAMAP rule MF_00383
General rule information
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Accession | MF_00383 |
Dates | 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 41) |
Name | TF2B_arch |
Scope(s) |
Archaea |
Template(s) | P61998 (TF2B_PYRFU); P61999 (TF2B_PYRWO); [ Recover all ] |
Triggered by |
HAMAP; MF_00383 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | TF2B |
Protein name | RecName: Full=Transcription initiation factor IIB; Short=TFIIB; |
Gene name | Name=tfb; |
Comments
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FUNCTION | Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). |
SIMILARITY | Belongs to the TFIIB family. |
Keywords
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Transcription | |
Transcription regulation | |
Repeat | |
case <FTGroup:1> | |
Metal-binding | |
Zinc | |
end case |
Gene Ontology
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GO:0003700; Molecular function:DNA-binding transcription factor activity | |
case <FTGroup:1> | |
GO:0008270; Molecular function:zinc ion binding | |
end case | |
GO:0006355; Biological process:regulation of DNA-templated transcription | |
GO:0006352; Biological process:DNA-templated transcription initiation |
Cross-references
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Pfam | PF00382; TFIIB; 2; |
Pfam | PF08271; TF_Zn_Ribbon; 1; |
PRINTS | PR00685; TIFACTORIIB; 1; |
PROSITE | PS00782; TFIIB; 2; |
PROSITE | PS51134; ZF_TFIIB; 0-1; |
Features
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From: TF2B_PYRFU (P61998) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REPEAT | 114 | 197 | /note="1" | |||||||||
REPEAT | 210 | 291 | /note="2" | |||||||||
BINDING | 7 | 7 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 10 | 10 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 26 | 26 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 29 | 29 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 |
Additional information
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Size range | 287-339 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | Intein deleted in METJA |