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HAMAP rule MF_00383

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General rule information [?]

Accession MF_00383
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 41)
Name TF2B_arch
Scope(s) Archaea
Template(s) P61998 (TF2B_PYRFU); P61999 (TF2B_PYRWO); [ Recover all ]
Triggered by HAMAP; MF_00383 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TF2B
Protein name RecName: Full=Transcription initiation factor IIB;
                 Short=TFIIB;
Gene name Name=tfb;

Comments [?]

FUNCTIONStabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
SIMILARITYBelongs to the TFIIB family.

Keywords [?]


Gene Ontology [?]

GO:0003700; Molecular function:DNA-binding transcription factor activity
case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding
end case
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006352; Biological process:DNA-templated transcription initiation

Cross-references [?]

Pfam PF00382; TFIIB; 2;
Pfam PF08271; TF_Zn_Ribbon; 1;
PRINTS PR00685; TIFACTORIIB; 1;
PROSITE PS00782; TFIIB; 2;
PROSITE PS51134; ZF_TFIIB; 0-1;

Features [?]

From: TF2B_PYRFU (P61998)
Key From To Description Tag Condition FTGroup
REPEAT 114 197 /note="1"
REPEAT 210 291 /note="2"
BINDING 7 7 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1
BINDING 26 26 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1
BINDING 29 29 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1

Additional information [?]

Size range 287-339 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Intein deleted in METJA



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