HAMAP

Accession	MF_00393
Dates	1-JUN-2001 (Created) 13-DEC-2011 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_00393; [distribution of match scores in UniProtKB];[seed alignment for MF_00393]

Names

Glyc3P_acyltrans

Identifier

PLSB

Protein name

RecName: Full=Glycerol-3-phosphate acyltransferase; Short=GPAT; EC=2.3.1.15;

Gene name

plsB

CATALYTIC ACTIVITY: Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.

PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.

SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side (By similarity).

DOMAIN: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate (By similarity).

SIMILARITY: Belongs to the GPAT/DAPAT family.

Pfam	PF01553; Acyltransferase; 1;

Acyltransferase.

Cell inner membrane.

Cell membrane, Membrane, Phospholipid biosynthesis, Transferase.

GO:0004366; Molecular function: glycerol-3-phosphate O-acyltransferase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

From: PLSB_ECOLI (P0A7A7)
Key		From		To		Description		Condition		FTGroup
MOTIF		305		310		HXXXXD motif

Size range:	775-886 amino acids
Related UniRules:	None
Template:	P0A7A7 (PLSB_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong start in XANAC, XANCP and XYLFA. Second divergent plsB in MYCTU; not shown in alignment.