Annotation rule MF_00394
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General rule information [?]

Accession MF_00394
Dates 1-JUN-2001 (Created)
13-JUL-2012 (Last updated, Version 31)
Name NAD_Glyc3P_dehydrog
Scope Bacteria
Archaea
Template O29390 (GPDA_ARCFU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GPDA
Protein name
RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(P)+];
EC=1.1.1.94;
AltName: Full=NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
Gene name
gpsA

Comments [?]

Catalytic activity sn-glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H.
Subcellular location Cytoplasm (By similarity).
Pathway Membrane lipid metabolism; glycerophospholipid metabolism.
Similarity Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Keywords [?]


Gene Ontology [?]

GO:0047952; Molecular function: glycerol-3-phosphate dehydrogenase [NAD(P)+] activity.
GO:0046167; Biological process: glycerol-3-phosphate biosynthetic process.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF07479; NAD_Gly3P_dh_C; 1;
PF01210; NAD_Gly3P_dh_N; 1;
PIRSF PIRSF000114; Glycerol-3-P_dh; 1;
PRINTS PR00077; GPDHDRGNASE; 1;
PROSITE PS00957; NAD_G3PDH; 1;

Features [?]

From: GPDA_ECOLI (P0A6S7)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     12     17       NAD (By similarity)        
REGION     259     260       Substrate binding (By similarity)     R-N  
ACT_SITE     195     195       Proton acceptor (By similarity)     K  
BINDING     110     110       NAD; via amide nitrogen (By similarity)     K  
BINDING     110     110       Substrate (By similarity)     K  
BINDING     143     143       NAD; via amide nitrogen (By similarity)     [AS]  
BINDING     259     259       NAD (By similarity)     R  
BINDING     285     285       NAD (By similarity)     E  

Additional information [?]

Size range 297-369 amino acids
Related rules None
Fusion None