HAMAP

Accession	MF_00394
Dates	1-JUN-2001 (Created) 13-DEC-2011 (Last updated, Version 30)

Data class

Protein

Predictors

HAMAP; MF_00394; [distribution of match scores in UniProtKB];[seed alignment for MF_00394]

Names

NAD_Glyc3P_dehydrog

Identifier

GPDA

Protein name

RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(P)+]; EC=1.1.1.94; AltName: Full=NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;

Gene name

gpsA

CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

PATHWAY: Membrane lipid metabolism; glycerophospholipid metabolism.

SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Pfam	PF07479; NAD_Gly3P_dh_C; 1; PF01210; NAD_Gly3P_dh_N; 1;
PIRSF	PIRSF000114; Glycerol-3-P_dh; 1;
PRINTS	PR00077; GPDHDRGNASE; 1;
PROSITE	PS00957; NAD_G3PDH; 1;

Cytoplasm, Phospholipid biosynthesis, Oxidoreductase, NAD.

GO:0047952; Molecular function: glycerol-3-phosphate dehydrogenase [NAD(P)+] activity.
GO:0046167; Biological process: glycerol-3-phosphate biosynthetic process.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: GPDA_ECOLI (P0A6S7)
Key		From		To		Description		Condition		FTGroup
NP_BIND		12		17		NAD (By similarity)
REGION		259		260		Substrate binding (By similarity)		R-N
ACT_SITE		195		195		Proton acceptor (By similarity)		K
BINDING		110		110		NAD; via amide nitrogen (By similarity)		K
BINDING		110		110		Substrate (By similarity)		K
BINDING		143		143		NAD; via amide nitrogen (By similarity)		[AS]
BINDING		259		259		NAD (By similarity)		R
BINDING		285		285		NAD (By similarity)		E

Size range:	297-369 amino acids
Related UniRules:	None
Template:	O29390 (GPDA_ARCFU)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in MYCPA, MYCTU
Plasmid encoded:	None