HAMAP

Accession	MF_00406
Dates	1-JUN-2001 (Created) 9-JUN-2011 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00406; [distribution of match scores in UniProtKB];[seed alignment for MF_00406]

Names

FabZ

Identifier

FABZ

Protein name

RecName: Full=(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Short=(3R)-hydroxymyristoyl ACP dehydrase; EC=4.2.1.-;

Gene name

fabZ

FUNCTION: Involved in saturated fatty acids biosynthesis (By similarity).

SUBUNIT: Oligomer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

PTM: The N-terminus is blocked (By similarity).

SIMILARITY: Belongs to the thioester dehydratase family. FabZ subfamily.

Pfam	PF07977; FabA; 1;
TIGRFAMs	TIGR01750; FabZ; 1;

Cytoplasm, Lyase, Lipid synthesis, Lipid A biosynthesis.

GO:0016836; Molecular function: hydro-lyase activity.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: FABZ_ECOLI (P0A6Q6)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		54		54		By similarity		H

Size range:	132-181 amino acids
Related UniRules:	MF_00405 (FABA)
Template:	P0A6Q6 (FABZ_ECOLI)
Scope:	Bacteria
Fusion:	Nter: MF_00388 (lpxC); Cter: None
Duplicate:	in LACLA
Plasmid encoded:	None
Comments:	Possible wrong start in SYNY3