HAMAP rule MF_00422
General rule information
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| Accession | MF_00422 |
| Dates | 11-JUL-2001 (Created)
1-JUN-2023 (Last updated, Version 34) |
| Name | SecE |
| Scope(s) |
Archaea Bacteria |
| Template(s) | D0VWU4 (SECE_AQUAE); P0AG96 (SECE_ECOLI); P35874 (SECE_THEMA); P38383 (SECE_THET8); Q57817 (SECE_METJA); [ Recover all ] |
| Triggered by |
HAMAP; MF_00422 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | SECE |
| case <OC:Bacteria> | |
| RecName: Full=Protein translocase subunit SecE; | |
| else case <OC:Archaea> | |
| RecName: Full=Protein translocase subunit SecE;<br /> AltName: Full=Protein transport protein Sec61 gamma subunit homolog; | |
| end case | |
| Gene name | Name=secE; |
Comments
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| FUNCTION | Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. |
| case <OC:Bacteria> | |
| SUBUNIT | Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA. |
| else case <OC:Archaea> | |
| SUBUNIT | Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved. |
| end case | |
| case (<OC:Cyanobacteriota> and not <OC:Gloeobacter>) and <Feature:Transmembrane==1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. Cellular thylakoid membrane; Single-pass membrane protein. |
| else case (<OC:Cyanobacteriota> and not <OC:Gloeobacter>) and <Feature:Transmembrane>1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. Cellular thylakoid membrane; Multi-pass membrane protein. |
| else case <OC:Gloeobacter> and <Feature:Transmembrane==1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| else case <OC:Gloeobacter> and <Feature:Transmembrane>1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| else case (not defined <Property:Membrane> or <Property:Membrane=1>) and <Feature:Transmembrane==1> | |
| SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
| else case (not defined <Property:Membrane> or <Property:Membrane=1>) and <Feature:Transmembrane>1> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| else case <Property:Membrane=2> and <Feature:Transmembrane==1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| else case <Property:Membrane=2> and <Feature:Transmembrane>1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the SecE/SEC61-gamma family. |
Keywords
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| case <OC:Cyanobacteriota> and not <OC:Gloeobacter> | |
| Cell membrane | |
| Cell inner membrane | |
| Thylakoid | |
| else case <OC:Gloeobacter> | |
| Cell membrane | |
| Cell inner membrane | |
| else case not defined <Property:Membrane> or <Property:Membrane=1> | |
| Cell membrane | |
| else case <Property:Membrane=2> | |
| Cell membrane | |
| Cell inner membrane | |
| end case | |
| Membrane | |
| Protein transport | |
| Translocation | |
| Transmembrane | |
| Transmembrane helix | |
| Transport | |
Gene Ontology
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| GO:0008320; Molecular function:protein transmembrane transporter activity | |
| GO:0009306; Biological process:protein secretion | |
| GO:0065002; Biological process:intracellular protein transmembrane transport | |
| GO:0006605; Biological process:protein targeting | |
| case <OCellular component:Bacteria> | |
| GO:0043952; Biological process:protein transport by the Sec complex | |
| end case | |
| case <OCellular component:Cyanobacteriota> and not <OC:Gloeobacter> | |
| GO:0042651; Cellular component:thylakoid membrane | |
| end case | |
| GO:0005886; Cellular component:plasma membrane | |
Cross-references
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| PROSITE | PS01067; SECE_SEC61G; 1; |
| Pfam | PF00584; SecE; 1; |
| PRINTS | PR01650; SECETRNLCASE; 1; |
| NCBIfam | TIGR00964; secE_bact; 1; |
| NCBIfam | TIGR00327; secE_euk_arch; 1; |
| General | Transmembrane; -; 1-3; |
Features
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Additional information
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| Size range | 57-162 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |