HAMAP

Accession	MF_00425
Dates	13-JUL-2001 (Created) 9-JUN-2011 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_00425; [distribution of match scores in UniProtKB];[seed alignment for MF_00425]

Names

NqrA

Identifier

NQRA

Protein name

RecName: Full=Na(+)-translocating NADH-quinone reductase subunit A; Short=Na(+)-NQR subunit A; Short=Na(+)-translocating NQR subunit A; EC=1.6.5.-; AltName: Full=NQR complex subunit A; AltName: Full=NQR-1 subunit A;

Gene name

nqrA

FUNCTION: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity).

CATALYTIC ACTIVITY: NADH + ubiquinone + Na(+)(In) = NAD(+) + ubiquinol + Na(+)(Out).

SUBUNIT: Composed of six subunits; nqrA, nqrB, nqrC, nqrD, nqrE and nqrF (By similarity).

SIMILARITY: Belongs to the nqrA family.

Pfam	PF05896; NQRA; 1;
TIGRFAMs	TIGR01936; NqrA; 1;

Oxidoreductase, NAD, Ubiquinone, Transport, Ion transport, Sodium, Sodium transport.

GO:0016655; Molecular function: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.

Size range:	443-467 amino acids
Related UniRules:	None
Template:	Q56586 (NQRA_VIBAL)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None