HAMAP

Accession	MF_00428
Dates	16-JUL-2001 (Created) 9-JUN-2011 (Last updated, Version 31)

Data class

Protein

Predictors

HAMAP; MF_00428; [distribution of match scores in UniProtKB];[seed alignment for MF_00428]

Names

NqrD

Identifier

NQRD

Protein name

RecName: Full=Na(+)-translocating NADH-quinone reductase subunit D; Short=Na(+)-NQR subunit D; Short=Na(+)-translocating NQR subunit D; EC=1.6.5.-; AltName: Full=NQR complex subunit D; AltName: Full=NQR-1 subunit D;

Gene name

nqrD

FUNCTION: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity).

CATALYTIC ACTIVITY: NADH + ubiquinone + Na(+)(In) = NAD(+) + ubiquinol + Na(+)(Out).

SUBUNIT: Composed of six subunits; nqrA, nqrB, nqrC, nqrD, nqrE and nqrF (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Potential).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (Potential).

SIMILARITY: Belongs to the nqrDE/rnfAE family.

Pfam	PF02508; Rnf-Nqr; 1;
PIRSF	PIRSF006102; NQR_DE; 1;
TIGRFAMs	TIGR01939; NqrD; 1;
General	Transmembrane; -; 5-7; trigger=Yes;

Oxidoreductase, NAD, Ubiquinone, Transport, Ion transport, Sodium, Sodium transport, Cell membrane, Membrane, Transmembrane.

Cell inner membrane.

Transmembrane helix.

GO:0016655; Molecular function: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.
GO:0005886; Cellular component: plasma membrane.

Size range:	208-224 amino acids
Related UniRules:	MF_00429 (NQRE)
Template:	Q57095 (NQRD_VIBAL)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None