HAMAP rule MF_00461
General rule information
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| Accession | MF_00461 |
| Dates | 16-OCT-2001 (Created)
1-JUN-2023 (Last updated, Version 44) |
| Name | RsxC_RnfC |
| Scope(s) |
Archaea Bacteria |
| Template(s) | P77611 (RSXC_ECOLI); Q52716 (RNFC_RHOCA); D5ARZ1 (RNFC_RHOCB); H6LC32 (RNFC_ACEWD); D8GR66 (RNFC_CLOLD); A0A0H3AJC2 (RNFC_VIBC3); Q8TSY4 (RNFC_METAC); [ Recover all ] |
| Triggered by |
HAMAP; MF_00461 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| Identifier | RSXC |
| Protein name | RecName: Full=Ion-translocating oxidoreductase complex subunit C; EC=7.-.-.-; AltName: Full=Rsx electron transport complex subunit C; |
| Gene name | Name=rsxC; |
| else | |
| Identifier | RNFC |
| Protein name | RecName: Full=Ion-translocating oxidoreductase complex subunit C; EC=7.-.-.-; AltName: Full=Rnf electron transport complex subunit C; |
| Gene name | Name=rnfC; |
| end case | |
Comments
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| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| FUNCTION | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. |
| else | |
| FUNCTION | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. |
| end case | |
| COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 2 [4Fe-4S] clusters per subunit.; |
| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| SUBUNIT | The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG. |
| else case <OC:Bacteria> | |
| SUBUNIT | The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. |
| else case <OC:Archaea> | |
| SUBUNIT | The Rnf complex is probably composed of eight subunits, including RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. |
| end case | |
| case (<OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Paracoccaceae> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
| else case <OC:Paracoccaceae> | |
| SUBCELLULAR LOCATION | Cellular chromatophore membrane; Peripheral membrane protein. |
| else | |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| end case | |
| SIMILARITY | Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. |
Keywords
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| 4Fe-4S | |
| case (<OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Paracoccaceae> | |
| Cell inner membrane | |
| end case | |
| case not <OC:Paracoccaceae> | |
| Cell membrane | |
| end case | |
| Electron transport | |
| Iron | |
| Iron-sulfur | |
| Membrane | |
| Metal-binding | |
| case <OC:Paracoccaceae> | |
| Nitrogen fixation | |
| end case | |
| Repeat | |
| <a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
| Transport | |
Gene Ontology
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| GO:0022900; Biological process:electron transport chain | |
| case <OCellular component:Paracoccaceae> | |
| GO:0009399; Biological process:nitrogen fixation | |
| end case | |
| case not <OCellular component:Paracoccaceae> | |
| GO:0005886; Cellular component:plasma membrane | |
| end case | |
Cross-references
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| Pfam | PF01512; Complex1_51K; 1; |
| Pfam | PF00037; Fer4; 2; |
| PRINTS | PR00353; 4FE4SFRDOXIN; 1; |
| NCBIfam | TIGR01945; rnfC; 1; |
| PROSITE | PS00198; 4FE4S_FER_1; 2; |
| PROSITE | PS51379; 4FE4S_FER_2; 2; |
Features
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| From: RNFC_RHOCA (Q52716) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 381 | 381 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | ||||||||
| BINDING | 384 | 384 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | ||||||||
| BINDING | 387 | 387 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | ||||||||
| BINDING | 391 | 391 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | ||||||||
| BINDING | 420 | 420 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | ||||||||
| BINDING | 423 | 423 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | ||||||||
| BINDING | 426 | 426 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | ||||||||
| BINDING | 430 | 430 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | ||||||||
Additional information
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| Size range | 400-1000 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Highly divergent C-terminal sequences. |