HAMAP

Accession	MF_00472
Dates	24-OCT-2001 (Created) 13-DEC-2011 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_00472; [distribution of match scores in UniProtKB];[seed alignment for MF_00472]

Names

UbiG

Identifier

UBIG

Protein name

RecName: Full=3-demethylubiquinone-9 3-methyltransferase; EC=2.1.1.64; AltName: Full=2-polyprenyl-6-hydroxyphenyl methylase; EC=2.1.1.222; AltName: Full=3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; Short=DHHB methyltransferase;

Gene name

ubiG

FUNCTION: Non-specific O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway (By similarity).

CATALYTIC ACTIVITY: S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n.

CATALYTIC ACTIVITY: S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.

PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.

SIMILARITY: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Pfam	PF01209; Ubie_methyltran; 1;

Ubiquinone biosynthesis, Transferase, Methyltransferase, S-adenosyl-L-methionine.

GO:0008689; Molecular function: 3-demethylubiquinone-9 3-O-methyltransferase activity.
GO:0006744; Biological process: ubiquinone biosynthetic process.

Size range:	232-261 amino acids
Related UniRules:	None
Template:	P17993 (UBIG_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None