HAMAP

Accession	MF_00475
Dates	25-OCT-2001 (Created) 30-MAY-2011 (Last updated, Version 22)

Data class

Protein

Predictors

HAMAP; MF_00475; [distribution of match scores in UniProtKB];[seed alignment for MF_00475]

Names

Trp_repressor

Identifier

TRPR

Protein name

RecName: Full=Trp operon repressor;

Protein name

RecName: Full=Trp operon repressor homolog;

Gene name

trpR

FUNCTION: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity).

FUNCTION: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity).

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the trpR family.

Pfam	PF01371; Trp_repressor; 1;

Cytoplasm, Transcription, Transcription regulation, Repressor, DNA-binding.

GO:0003677; Molecular function: DNA binding.
GO:0045892; Biological process: negative regulation of transcription, DNA-dependent.
GO:0005737; Cellular component: cytoplasm.

From: TRPR_ECOLI (P0A881)
Key		From		To		Description		Condition		FTGroup
DNA_BIND		68		91		By similarity

Size range:	92-125 amino acids
Related UniRules:	None
Template:	P0A881 (TRPR_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None