HAMAP

Accession	MF_00492
Dates	28-NOV-2001 (Created) 21-FEB-2011 (Last updated, Version 27)

Data class

Protein

Predictors

HAMAP; MF_00492; [distribution of match scores in UniProtKB];[seed alignment for MF_00492]

Names

Transaldolase_1

Identifier

TAL

Protein name

RecName: Full=Transaldolase; EC=2.2.1.2;

Gene name

tal

FUNCTION: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity).

CATALYTIC ACTIVITY: Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.

PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the transaldolase family. Type 1 subfamily.

Pfam	PF00923; Transaldolase; 1;
PROSITE	PS01054; TRANSALDOLASE_1; 1; PS00958; TRANSALDOLASE_2; 1;

Cytoplasm, Transferase, Pentose shunt.

GO:0004801; Molecular function: sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity.
GO:0006098; Biological process: pentose-phosphate shunt.
GO:0005737; Cellular component: cytoplasm.

From: TALB_ECOLI (P0A870)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		132		132		By similarity		K

Size range:	307-397 amino acids
Related UniRules:	MF_00493 (TAL); MF_00494 (TAL); MF_00496 (FSA)
Template:	P0A867 (TALA_ECOLI); P0A870 (TALB_ECOLI): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: <Unknown>
Duplicate:	in ECOLI, ECOL6, ECO57, ERWCT, PASMU, SALCH, SALPA, SALTI, SALTY, SHIFL, SHISS
Plasmid encoded:	None
Comments:	C-terminal domain that contains 2 EF-hands in GLOVI, PROMM, THEEB, SYNPX, SYNY3