HAMAP rule MF_00501
General rule information
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| Accession | MF_00501 |
| Dates | 8-DEC-2001 (Created)
22-SEP-2023 (Last updated, Version 40) |
| Name | Ribosomal_bL31_1 |
| Scope(s) |
Bacteria Plastid |
| Template(s) | Q03223 (RL31_BACSU); Q9RW44 (RL31_DEIRA); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_00501 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL31 |
| Protein name | RecName: Full=Large ribosomal subunit protein bL31; |
| Gene name | Name=rpmE; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL31 |
| Protein name | RecName: Full=Large ribosomal subunit protein bL31; |
| Gene name | Name=rpmE; Synonyms=rpl31; |
| else case <OG:Chloroplast> | |
| Identifier | RK31 |
| Protein name | RecName: Full=Large ribosomal subunit protein bL31c; |
| Gene name | Name=rpl31; |
| end case | |
Comments
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| FUNCTION | Binds the 23S rRNA. |
| case <FTGroup:1> | |
| COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.; |
| end case | |
| SUBUNIT | Part of the 50S ribosomal subunit. |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. |
Keywords
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| case <FT:5> | |
| Acetylation | |
| end case | |
| Ribonucleoprotein | |
| Ribosomal protein | |
| RNA-binding | |
| rRNA-binding | |
| case <FTGroup:1> | |
| Zinc | |
| Metal-binding | |
| end case | |
Gene Ontology
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| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF01197; Ribosomal_L31; 1; |
| PRINTS | PR01249; RIBOSOMALL31; 1; |
| NCBIfam | TIGR00105; L31; 1; |
| PROSITE | PS01143; RIBOSOMAL_L31; 1; |
Features
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| From: RL31_BACSU (Q03223) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 16 | 16 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 18 | 18 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 36 | 36 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 39 | 39 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| From: RL31_ECOLI (P0A7M9) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Escherichia> or <OC:Shigella> | ||||||||||||
| MOD_RES | 8 | 8 | /note="N6-acetyllysine" | K | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 65-97 amino acids |
| Related rules |
MF_00502 |
| Fusion | Nter: None Cter: <Unknown> |
| Comments | Fused with an unknown domain in ANADE. In some bacteria, for example E.coli and B.subtilis, there are paralogous RL31 proteins. In most bacteria with both proteins the protein that corresponds to this family (RL31, rpmE) is thought to be able to bind zinc, while the other member (RL31B, MF_00502, rpmE2) is not able to bind zinc. It has been suggested based on this observation and experiments in B. subtilis that the non-zinc-binding protein will only be made under conditions of zinc-starvation, allowing the cell to economize on the trace metal, see: PubMed=11574053; Makarova K.S., Ponomarev V.A., Koonin E.V.; "Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins."; Genome Biol. 2:RESEARCH 0033-RESEARCH 0033(2001). and PubMed=12904577; DOI=10.1073/pnas.1733691100; Panina E.M., Mironov A.A., Gelfand M.S.; "Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins."; Proc. Natl. Acad. Sci. U.S.A. 100:9912-9917(2003). |