Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP annotation rule: MF_00501
Send feedback new

General rule information

Accession MF_00501
Dates 8-DEC-2001 (Created)
25-NOV-2009 (Last updated, Version 28)
Data class Protein
Predictors HAMAP; MF_00501; [distribution of match scores in UniProtKB];[seed alignment for MF_00501]
Names Ribosomal_L31_1


Propagated annotation

Identifier, protein and gene names

case <OC:Bacteria> and not <OC:Cyanobacteria>
Identifier RL31
Protein name
RecName: Full=50S ribosomal protein L31;
Gene name rpmE

else case <OC:Cyanobacteria>
Identifier RL31
Protein name
RecName: Full=50S ribosomal protein L31;
Gene name rpmE, rpl31

else case <OG:Chloroplast>
Identifier RK31
Protein name
RecName: Full=50S ribosomal protein L31, chloroplastic;
Gene name rpl31
end case

Comments
FUNCTION: Binds the 23S rRNA (By similarity).

case <FTGroup:1>
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
end case

SUBUNIT: Part of the 50S ribosomal subunit (By similarity).

case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the ribosomal protein L31P family. Type A subfamily.
Cross-references
Pfam PF01197; Ribosomal_L31; 1;
PRINTS PR01249; RIBOSOMALL31; 1;
TIGRFAMs TIGR00105; L31; 1;
PROSITE PS01143; RIBOSOMAL_L31; 1;
Keywords

case <FT:5>
Acetylation.
end case

Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding.

case <FTGroup:1>
Zinc, Metal-binding.
end case

Gene Ontology
GO:0006412; Biological process: translation.

case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Features
From: RL31_BACSU (Q03223)
Key     From     To       Description   Condition   FTGroup
METAL (Optional)     16     16       Zinc (By similarity)   C   1
METAL (Optional)     18     18       Zinc (By similarity)   C   1
METAL (Optional)     36     36       Zinc (By similarity)   C   1
METAL (Optional)     39     39       Zinc (By similarity)   C   1
case <OC:Escherichia> or <OC:Shigella>
From: RL31_ECOLI (P0A7M9)
Key     From     To       Description   Condition   FTGroup
MOD_RES     8     8       N6-acetyllysine (By similarity)   K  
end case



Additional information

Size range: 65-97 amino acids
Related UniRules: MF_00502 (RL31B (supersedes the current rule))
Template: Q03223 (RL31_BACSU); Q9RW44 (RL31_DEIRA): [Recover all]
Scope: Bacteria
Plastid
Fusion: Nter: None; Cter: <Unknown>
Duplicate: None
Plasmid encoded: None
Comments: Fused with an unknown domain in ANADE. In some bacteria, for example E.coli and B.subtilis, there are paralogous RL31 proteins. In most bacteria with both proteins the protein that corresponds to this family (RL31, rpmE) is thought to be able to bind zinc, while the other member (RL31B, MF_00502, rpmE2) is not able to bind zinc. It has been suggested based on this observation and experiments in B. subtilis that the non-zinc-binding protein will only be made under conditions of zinc-starvation, allowing the cell to economize on the trace metal, see: PubMed=11574053; Makarova K.S., Ponomarev V.A., Koonin E.V.; "Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins."; Genome Biol. 2:RESEARCH 0033-RESEARCH 0033(2001). and PubMed=12904577; DOI=10.1073/pnas.1733691100; Panina E.M., Mironov A.A., Gelfand M.S.; "Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins."; Proc. Natl. Acad. Sci. U.S.A. 100:9912-9917(2003).

View rule in raw text format (no links)



UniProtKB rule member sequences