HAMAP

Accession	MF_00513
Dates	19-DEC-2001 (Created) 25-NOV-2009 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_00513; [distribution of match scores in UniProtKB];[seed alignment for MF_00513]

Names

IciA

Identifier

ICIA

Protein name

RecName: Full=Chromosome initiation inhibitor; AltName: Full=OriC replication inhibitor;

Gene name

iciA

FUNCTION: Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity).

SIMILARITY: Contains 1 HTH lysR-type DNA-binding domain.

Pfam	PF00126; HTH_1; 1;
PRINTS	PR00039; HTHLYSR; 1;
PROSITE	PS50931; HTH_LYSR; 1; trigger=PRU00253;

DNA-binding, Transcription, Transcription regulation.

GO:0003677; Molecular function: DNA binding.
GO:0008156; Biological process: negative regulation of DNA replication.

From: ICIA_ECOLI (P0A8S1)
Key		From		To		Description		Condition		FTGroup
DNA_BIND		21		40		H-T-H motif (By similarity)

Size range:	293-302 amino acids
Related UniRules:	None
Template:	P0A8S1 (ICIA_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None