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HAMAP annotation rule: MF_00530
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General rule information

Accession MF_00530
Dates 20-JAN-2002 (Created)
16-AUG-2010 (Last updated, Version 42)
Data class Protein
Predictors HAMAP; MF_00530; [distribution of match scores in UniProtKB];[seed alignment for MF_00530]
Names ATP_synth_epsil_bac


Propagated annotation

Identifier, protein and gene names
Identifier ATPE

case <OC:Bacteria>
Protein name
RecName: Full=ATP synthase epsilon chain;
AltName: Full=ATP synthase F1 sector epsilon subunit;
AltName: Full=F-ATPase epsilon subunit;
Gene name atpC

else case <OG:Chloroplast>
Protein name
RecName: Full=ATP synthase epsilon chain, chloroplastic;
AltName: Full=ATP synthase F1 sector epsilon subunit;
AltName: Full=F-ATPase epsilon subunit;
Gene name atpE
end case

Comments
FUNCTION: Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity).
SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c (By similarity).

case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane; Peripheral membrane protein (By similarity).

else case <OC:Cyanobacteria> and not <OC:Gloeobacter>
SUBCELLULAR LOCATION: Cellular thylakoid membrane; Peripheral membrane protein (By similarity).

else case <OC:Gloeobacter>
SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity).

else case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity).
end case

SIMILARITY: Belongs to the ATPase epsilon chain family.
Cross-references
Pfam PF00401; ATP-synt_DE; 1;
PF02823; ATP-synt_DE_N; 1;
Keywords
ATP synthesis, CF(1), Transport, Ion transport, Hydrogen ion transport.

case <OG:Chloroplast> or <OC:Cyanobacteria> and not <OC:Gloeobacter>
Thylakoid.

else case <OC:Gloeobacter>
Cell membrane, Cell inner membrane.

else case not defined <Property:Membrane> or <Property:Membrane=1>
Cell membrane.

else case <Property:Membrane=2>
Cell membrane, Cell inner membrane.
end case

Membrane.
Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0046933; Molecular function: hydrogen ion transporting ATP synthase activity, rotational mechanism.
GO:0042777; Biological process: plasma membrane ATP synthesis coupled proton transport.

case <OG:Chloroplast>
GO:0009535; Cellular component: chloroplast thylakoid membrane.

else case <OC:Cyanobacteria> and not <OC:Gloeobacter>
GO:0042651; Cellular component: thylakoid membrane.

else
GO:0005886; Cellular component: plasma membrane.
end case



Additional information

Size range: 108-152 amino acids
Related UniRules: None
Template: P0A6E6 (ATPE_ECOLI)
Scope: Bacteria
Plastid
Fusion: Nter: None; Cter: None
Duplicate: in BURCA, BURXL, METCA, NITHX, PELCD, PHOPR, RHOS4, THIDA
Plasmid encoded: in RHOS4
Comments: Divergent CAUCR and CHLLI not shown in alignment. ACEWO and PROMO are sodium-specific; it is not possible to distinguish proton-depedent ATPase subunits from sodium-dependent ones. FRASC and NOVAD are 87 residues long and marked as atypical.

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UniProtKB rule member sequences