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HAMAP rule MF_00543

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General rule information [?]

Accession MF_00543
Dates 8-MAR-2002 (Created)
1-JUN-2023 (Last updated, Version 24)
Name Tyr_phenol_lyase
Scope(s) Bacteria
Template(s) P31013 (TPL_CITFR); [ Recover all ]
Triggered by HAMAP; MF_00543 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TPL
Protein name RecName: Full=Tyrosine phenol-lyase;
                 EC=4.1.99.2;
AltName: Full=Beta-tyrosinase;
Gene name Name=tpl;

Comments [?]

CATALYTIC ACTIVITY Reaction=H2O + L-tyrosine = NH4(+) + phenol + pyruvate; Xref=Rhea:RHEA:21704, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15882, ChEBI:CHEBI:28938, ChEBI:CHEBI:58315; EC=4.1.99.2;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
SUBUNITHomotetramer.
SIMILARITYBelongs to the beta-eliminating lyase family.

Keywords [?]


Gene Ontology [?]

GO:0050371; Molecular function:tyrosine phenol-lyase activity

Cross-references [?]

Pfam PF01212; Beta_elim_lyase; 1;
PIRSF PIRSF001386; Trpase; 1;
NCBIfam TIGR02618; Tyr_phenol_ly; 1;
PROSITE PS00853; BETA_ELIM_LYASE; 1;

Features [?]

From: TPL_CITFR (P31013)
Key From To Description Tag Condition FTGroup
MOD_RES 257 257 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 456-473 amino acids
Related rules MF_00544
Fusion Nter: None Cter: None



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